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公开(公告)号:US20070128157A1
公开(公告)日:2007-06-07
申请号:US10582316
申请日:2004-08-13
申请人: Xin Lu , Elizabeth Slee
发明人: Xin Lu , Elizabeth Slee
CPC分类号: C07K14/4702 , C07K14/525 , C12Q1/6886 , C12Q2600/136 , C12Q2600/178 , Y10S530/828
摘要: We describe a polypeptide which binds and modulates the activity of a tumour suppressor polypeptide, for example p53; a nucleic acid molecule encoding said protein and screening methods which modulate the binding activity of said polypeptide for its target polypeptide(s).
摘要翻译: 我们描述了结合和调节肿瘤抑制多肽的活性的多肽,例如p53; 编码所述蛋白质的核酸分子和调节所述多肽对其靶多肽的结合活性的筛选方法。
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公开(公告)号:US20100047868A1
公开(公告)日:2010-02-25
申请号:US12537050
申请日:2009-08-06
申请人: Xin Lu , Elizabeth Slee
发明人: Xin Lu , Elizabeth Slee
CPC分类号: C07K14/4702 , C07K14/525 , C12Q1/6886 , C12Q2600/136 , C12Q2600/178 , Y10S530/828
摘要: We describe a polypeptide which binds and modulates the activity of a tumour suppressor polypeptide, for example p53; a nucleic acid molecule encoding said protein and screening methods which modulate the binding activity of said polypeptide for its target polypeptide(s).
摘要翻译: 我们描述了结合和调节肿瘤抑制多肽的活性的多肽,例如p53; 编码所述蛋白质的核酸分子和调节所述多肽对其靶多肽的结合活性的筛选方法。
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公开(公告)号:US07645859B2
公开(公告)日:2010-01-12
申请号:US10582316
申请日:2004-08-13
申请人: Xin Lu , Elizabeth Slee
发明人: Xin Lu , Elizabeth Slee
IPC分类号: C07K14/00
CPC分类号: C07K14/4702 , C07K14/525 , C12Q1/6886 , C12Q2600/136 , C12Q2600/178 , Y10S530/828
摘要: We describe a polypeptide which binds and modulates the activity of a tumour suppressor polypeptide, for example p53; a nucleic acid molecule encoding said protein and screening methods which modulate the binding activity of said polypeptide for its target polypeptide(s).
摘要翻译: 我们描述了结合和调节肿瘤抑制多肽的活性的多肽,例如p53; 编码所述蛋白质的核酸分子和调节所述多肽对其靶多肽的结合活性的筛选方法。
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