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1.
公开(公告)号:US06482924B1
公开(公告)日:2002-11-19
申请号:US09461920
申请日:1999-12-15
IPC分类号: C07K100
CPC分类号: C12N9/12 , A61K39/00 , C07K14/20 , C12N9/1048 , C12N9/1051 , Y02A50/48 , Y10S530/806 , Y10S530/825
摘要: Four antigenic preparations are provided, each of which contains a different protein from Leptospira which can be used immunologically in vaccines for leptospirosis caused by this organism. Also provided in the invention are polynucleotides encoding these four proteins and antibodies which bind the proteins for use in the diagnosis of leptospirosis.
摘要翻译: 提供四种抗原制剂,每种抗原制剂含有来自钩端螺旋体的不同蛋白质,其可以在疫苗中免疫用于由该生物体引起的钩端螺旋体病。 本发明还提供编码这四种蛋白质的多核苷酸和结合蛋白质的抗体,用于诊断钩端螺旋体病。
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2.
公开(公告)号:US06800734B2
公开(公告)日:2004-10-05
申请号:US10255018
申请日:2002-09-25
IPC分类号: C07K100
CPC分类号: C12N9/12 , A61K39/00 , C07K14/20 , C12N9/1048 , C12N9/1051 , Y02A50/48 , Y10S530/806 , Y10S530/825
摘要: Four antigenic preparations are provided, each of which contains a different protein from Leptospira which can be used immunologically in vaccines for leptospirosis caused by this organism. Also provided in the invention are polynucleotides encoding these four proteins and antibodies which bind the proteins for use in the diagnosis of leptospirosis.
摘要翻译: 提供四种抗原制剂,每种抗原制剂含有来自钩端螺旋体的不同蛋白质,其可以在疫苗中免疫用于由该生物体引起的钩端螺旋体病。 本发明还提供编码这四种蛋白质的多核苷酸和结合蛋白质的抗体,用于诊断钩端螺旋体病。
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