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公开(公告)号：US20050020484A1
公开(公告)日：2005-01-27
申请号：US10500245
申请日：2002-12-27
CPC分类号： A61K38/38 , A23L33/19 , A23V2002/00 , A61K38/40 , A23V2250/54248 , A23V2250/5424 , A23V2250/304 , A23V2200/332 , A23V2200/328 , A61K2300/00
摘要： The present invention provides a pharmaceutical composition having at least one kind to be selected from the group consisting of a lactoferrin group protein comprising lactoferrin and conalbumin, and an enzymatically decomposed product of the lactoferrin group protein comprising peptides corresponding to lactoferricin and lactoferricin of conalbumin an active ingredient. The composition of the present invention can be used as an agent for improving lipid metabolism. Further, it is useful for treating hypercholesterolemia, hyper-neutral lipidemia, hyper-low density lipoprotein (LDL) cholesterolemia, hypo-high density lipoprotein (HDL) cholesterolemia, obesity, fatty liver and cholesterol gallstone and lifestyle-related diseases such as severe obesity, hyperlipidemia, hypertension and type II diabetes. The composition of the present invention can improve basal metabolic rate.
摘要翻译： 本发明提供一种药物组合物，其具有至少一种选自包含乳铁蛋白和对照蛋白的乳铁蛋白基团蛋白质的组合物，以及乳铁蛋白基团蛋白质的酶促分解产物，其包含对应于乳酸铁蛋白的乳铁蛋白和乳铁蛋白的活性成分 成分。 本发明的组合物可以用作改善脂质代谢的药剂。 此外，它可用于治疗高胆固醇血症，超中性脂质血症，高低密度脂蛋白（LDL）胆固醇血症，低密度脂蛋白（HDL）胆固醇血症，肥胖症，脂肪肝和胆固醇胆结石以及生活方式相关疾病如严重肥胖 ，高脂血症，高血压和II型糖尿病。 本发明的组合物可以改善基础代谢率。
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公开(公告)号：US20050119162A1
公开(公告)日：2005-06-02
申请号：US10502209
申请日：2003-01-17
IPC分类号： A61K9/19 , A61K9/20 , A61K9/28 , A61K31/485 , A61K38/40 , A61P25/00 , A61P25/04 , A61P25/22 , A61P29/00 , A61P41/00 , A61P43/00
CPC分类号： A61K9/2866 , A61K9/19 , A61K9/2013 , A61K9/205 , A61K9/282 , A61K31/485 , A61K38/40 , A61K2300/00
摘要： The object of this invention is to provide a novel pharmaceutical composition for getting rid of pains and anxiety in patients. This invention relates to a pharmaceutical composition containing lactoferrin as an active ingredient. The composition of this invention is useful for treatment of at least one disease or condition selected from the group consisting of pains, including the phase 1 pain and the phase 2 pain, anxiety and stress. The composition is particularly beneficial to alleviating or getting rid of the pain and anxiety which significantly lower quality of life of patients with end-stage cancer. The composition of this invention is also useful for treatment of pains, including the phase 1 pain and the phase 2 pain, and inflammation which accompany arthritis or diseases in the junctions of bones (e.g. rheumatoid arthritis, osteoarthritis, frozen shoulder, sports injuries such as tennis elbow and baseball shoulder, and low back pain).
摘要翻译： 本发明的目的是提供一种用于消除患者的疼痛和焦虑的新型药物组合物。 本发明涉及含有乳铁蛋白作为活性成分的药物组合物。 本发明的组合物可用于治疗选自疼痛，包括1期疼痛和2期疼痛，焦虑和压力的至少一种疾病或病症。 该组合物特别有利于缓解或消除显着降低终末期癌症患者生活质量的疼痛和焦虑。 本发明的组合物还可用于治疗疼痛，包括1期疼痛和2期疼痛，以及伴随关节炎或骨骼关节疾病的炎症（例如类风湿性关节炎，骨关节炎，冷冻肩部，运动损伤如 网球肘和棒球肩膀，腰痛）。
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公开(公告)号：US08399414B2
公开(公告)日：2013-03-19
申请号：US10502209
申请日：2003-01-17
CPC分类号： A61K9/2866 , A61K9/19 , A61K9/2013 , A61K9/205 , A61K9/282 , A61K31/485 , A61K38/40 , A61K2300/00
摘要： The object of this invention is to provide a novel pharmaceutical composition for getting rid of pains and anxiety in patients. This invention relates to a pharmaceutical composition containing lactoferrin as an active ingredient. The composition of this invention is useful for treatment of at least one disease or condition selected from the group consisting of pains, including the phase 1 pain and the phase 2 pain, anxiety and stress. The composition is particularly beneficial to alleviating or getting rid of the pain and anxiety which significantly lower quality of life of patients with end-stage cancer. The composition of this invention is also useful for treatment of pains, including the phase 1 pain and the phase 2 pain, and inflammation which accompany arthritis or diseases in the junctions of bones (e.g. rheumatoid arthritis, osteoarthritis, frozen shoulder, sports injuries such as tennis elbow and baseball shoulder, and low back pain).
摘要翻译： 本发明的目的是提供一种用于消除患者的疼痛和焦虑的新型药物组合物。 本发明涉及含有乳铁蛋白作为活性成分的药物组合物。 本发明的组合物可用于治疗选自疼痛，包括1期疼痛和2期疼痛，焦虑和压力的至少一种疾病或病症。 该组合物特别有利于缓解或消除显着降低终末期癌症患者生活质量的疼痛和焦虑。 本发明的组合物还可用于治疗疼痛，包括1期疼痛和2期疼痛，以及伴随关节炎或骨骼关节疾病的炎症（例如类风湿性关节炎，骨关节炎，冷冻肩部，运动损伤如 网球肘和棒球肩膀，腰痛）。
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4.发明申请METHODS FOR IMPROVED LIPID METABOLISM AND BASAL METABOLIC RATE WITH LACTOFERRIN 审中-公开改进脂质代谢和基础代谢率的方法与LACTOFERRIN公开(公告)号：US20080014270A1
公开(公告)日：2008-01-17
申请号：US11832387
申请日：2007-08-01
CPC分类号： A61K38/38 , A23L33/19 , A23V2002/00 , A61K38/40 , A23V2250/54248 , A23V2250/5424 , A23V2250/304 , A23V2200/332 , A23V2200/328 , A61K2300/00
摘要： A pharmaceutical composition is provided having at least one kind to be selected from the group consisting of a lactoferrin group protein having lactoferrin and conalbumin, and an enzymatically decomposed product of the lactoferrin group protein having peptides corresponding to lactoferricin and lactoferricin of conalbumin as an active ingredient. The composition of the present invention can be used as an agent for improving lipid metabolism. Further, it is useful for treating hypercholesterolemia, hyper-neutral lipidemia, hyper-low density lipoprotein (LDL) cholesterolemia, hypo-high density lipoprotein (HDL) cholesterolemia, obesity, fatty liver and cholesterol gallstone and lifestyle-related diseases such as severe obesity, hyperlipidemia, hypertension and type II diabetes. The composition of the present invention can improve basal metabolic rate.
摘要翻译： 提供一种药物组合物，其具有至少一种选自具有乳铁蛋白和氨聚糖蛋白的乳铁蛋白基蛋白和乳铁蛋白基蛋白的酶促分解产物，所述乳铁蛋白基蛋白具有与对照乳头蛋白的乳铁蛋白和乳铁蛋白作为活性成分的肽 。 本发明的组合物可以用作改善脂质代谢的药剂。 此外，它可用于治疗高胆固醇血症，超中性脂质血症，高低密度脂蛋白（LDL）胆固醇血症，低密度脂蛋白（HDL）胆固醇血症，肥胖症，脂肪肝和胆固醇胆结石以及生活方式相关疾病如严重肥胖 ，高脂血症，高血压和II型糖尿病。 本发明的组合物可以改善基础代谢率。
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