Amphiphilic cyclodextrin derivatives, method for preparation thereof and uses thereof
    4.
    发明授权
    Amphiphilic cyclodextrin derivatives, method for preparation thereof and uses thereof 失效
    两亲环糊精衍生物,其制备方法和用途

    公开(公告)号:US07812152B2

    公开(公告)日:2010-10-12

    申请号:US10576346

    申请日:2004-10-21

    IPC分类号: A61K9/127 A61K31/724 A61K8/14

    摘要: The invention relates to cyclodextrin derivatives of formula (I): in which: R1=—NH-E-AA-(L1)p(L2)q where E=a linear or branched C1-C15 hydrocarbon-based group with, optionally, one or more hetero atoms; AA=the residue of an amino acid; L1 and L2=a C6-C24 hydrocarbon-based group with, optionally, one or more hetero atoms; p and q=0 or 1, at least one being ≠0; R2=H, —CH3, isopropyl, hydroxypropyl, sulphobutyl ether; R3=H or R2, except when R2=hydroxypropyl; all the R4=—OH or R2, except when R2=hydroxypropyl, or at least one of the R4=R1; n=5, 6 or 7. The invention also relates to a process for preparing them, and to inclusion complexes and organized surfactant systems comprising them.

    摘要翻译: 本发明涉及式(I)的环糊精衍生物:其中:R1 = -NH-E-AA-(L1)p(L2)q其中E =直链或支链C 1 -C 15烃基, 一个或多个杂原子; AA =氨基酸的残基; L1和L2 =具有任选的一个或多个杂原子的C 6 -C 24烃基; p和q = 0或1,至少一个≠0; R2 = H,-CH3,异丙基,羟丙基,磺丁基醚; R3 = H或R2,当R2 =羟丙基时; 所有的R4 = -OH或R2,除非R2 =羟丙基,或R4 = R1中至少一个; n = 5,6或7.本发明还涉及一种制备它们的方法,以及包含它们的包合物和有组织的表面活性剂体系。

    Amphiphilic cyclodextrin derivatives, method for preparation thereof and uses thereof
    6.
    发明申请
    Amphiphilic cyclodextrin derivatives, method for preparation thereof and uses thereof 失效
    两亲环糊精衍生物,其制备方法和用途

    公开(公告)号:US20070142324A1

    公开(公告)日:2007-06-21

    申请号:US10576346

    申请日:2004-10-21

    IPC分类号: A61K31/724 C08B30/18

    摘要: The invention relates to cyclodextrin derivatives of formula (I): in which: R1═—NH-E-AA-(L1)p(L2)q where E=a linear or branched Cl-Cl5 hydrocarbon-based group with, optionally, one or more hetero atoms; AA=the residue of an amino acid; L1 and L2=a C6-C24 hydrocarbon-based group with, optionally, one or more hetero atoms; p and q=0 or 1, at least one being ≠0; R2═H, —CH3, isopropyl, hydroxypropyl, sulphobutyl ether; R3═H or R2, except when R2=hydroxypropyl; all the R4═—OH or R2, except when R2=hydroxypropyl, or at least one of the R4═R1; n=5, 6 or 7. The invention also relates to a process for preparing them, and to inclusion complexes and organized surfactant systems comprising them.

    摘要翻译: 本发明涉及式(I)的环糊精衍生物:其中:R 1-NH-E-AA-(L 1) 其中E =直链或支链的C 1 -C 15烃基基团,任选地一个或多个杂原子(C 1 -C 6) 原子 AA =氨基酸的残基; 一个或多个基于烃的基团,其中任选地是一个或多个基于烃基的C 1 -C 12 - 更多的杂原子 p和q = 0或1,至少一个<> 0; R 2,H 3,CH 3,异丙基,羟丙基,磺基丁基醚; 除了R 2 =羟丙基之外,R 3是H或R 2, 所有的R 4 OH或R 2,除了当R 2 =羟丙基,或R 4中的至少一个时, -R <1> ; n = 5,6或7.本发明还涉及一种制备它们的方法,以及包含它们的包合物和有组织的表面活性剂体系。