Isolation and purification of the R18 antigen of HTLV-III
    1.
    发明授权
    Isolation and purification of the R18 antigen of HTLV-III 失效
    分离和纯化HTLV-III的R18抗原

    公开(公告)号:US5063053A

    公开(公告)日:1991-11-05

    申请号:US556999

    申请日:1990-07-25

    IPC分类号: A61K38/00 C07K14/16 C07K16/10

    摘要: The isolation and purification of a newly discovered gene of the AIDS virus, HTLV-III, which encodes a portein which is immunogenic and recognized by sera of some HTLV-III seropositive people. Furthermore, the gene is highly conserved among all known HTLV-III isolates and exhibits a polymorphism at the 3' end which distinguishes molecular clones of the HTLV-IIIB cell line from viral genomes of related viruses.

    摘要翻译: 分离和纯化新发现的艾滋病病毒基因HTLV-III,其编码一种免疫原性并被一些HTLV-III血清阳性人的血清识别的portein。 此外,该基因在所有已知的HTLV-III分离物中是高度保守的,并且在3'末端显示出多态性,其区分HTLV-IIIB细胞系的分子克隆与相关病毒的病毒基因组。