公开(公告)号：US20060110412A1

公开(公告)日：2006-05-25

申请号：US10529064

申请日：2003-06-10

申请人： Pierre Desmons ,  Jan Poolman ,  Ramon Barbera Morales ,  Francisco Dominguez Alvarez

发明人： Pierre Desmons ,  Jan Poolman ,  Ramon Barbera Morales ,  Francisco Dominguez Alvarez

IPC分类号： A61K39/095

CPC分类号： A61K39/095 ,  A61K2039/52 ,  C07K14/22

摘要： The present invention relates to vaccine compositions for the effective prevention of neisserial, preferably meningococcal, disease. The vaccine of the invention comprise a multivalent meningococcal bled composition comprising at least one bleb with homologous bactericidal activity which is derived from a meningococcal strain with a serosubtype that is prevalent in a country of use, and at least one bleb with heterologous bacterial activity which is derived from a meningococcal strain which need not have a serosubtype that is prevalent in the country of use.

摘要翻译： 本发明涉及用于有效预防奈瑟氏球菌，优选脑膜炎球菌病的疫苗组合物。 本发明的疫苗包含多价脑膜炎球菌疫苗组合物，其包含至少一种具有同源杀菌活性的泡沫，其具有在使用国家中普遍存在的血清型的脑膜炎球菌菌株，以及至少一种具有异源细菌活性的泡沫， 衍生自不需要在使用国家普遍存在的血清型的脑膜炎球菌菌株。