利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

3 条记录 (耗时 0.018 秒)

    Ruminal drug delivery device
    1.
    发明授权
    Ruminal drug delivery device 失效
    瘤胃药物输送装置

    公开(公告)号：US5431919A

    公开(公告)日：1995-07-11

    申请号：US81743

    申请日：1993-06-23

    申请人： Fred Maruyama ,  John P. Carr ,  James B. Eckenhoff

    发明人： Fred Maruyama ,  John P. Carr ,  James B. Eckenhoff

    IPC分类号： A61K9/00 ,  A61K9/24

    CPC分类号： A61K9/0004

    摘要： The present invention is concerned with improving the delivery of a drug from a ruminal delivery device to give a consistent delivery of drug to the ruminal environment. Thus, the invention is directed to an improved ruminal drug delivery device comprising a semipermeable membrane having an exit orifice and defining a compartment, the compartment containing a swellable osmotic agent expandable member, a drug to be dispensed, a density element and, optionally, a partition layer between the osmotic expandable member and the drug formulation, wherein the improvement comprises an essentially gas-impermeable barrier means that separates the density element from the other components within the delivery device for isolating gases evolved from the density element from the other components within the delivery device. The invention is also directed to methods and articles for providing a consistent delivery of drug from a ruminal drug delivery device.

    摘要翻译： 本发明涉及改善药物从瘤胃递送装置的递送以使药物向瘤胃环境的一致递送。 因此，本发明涉及一种改进的瘤胃药物递送装置，其包括具有出口孔并限定隔室的半透膜，所述隔室含有可溶胀渗透剂可膨胀构件，待分配药物，密度元件和任选地 渗透可膨胀构件和药物制剂之间的分隔层，其中改进包括基本上气体不可渗透的阻挡装置，其将密度元件与输送装置内的其它成分分离，用于将密度元素放出的气体与其中的其它成分分离 送货装置 本发明还涉及用于提供来自瘤胃药物递送装置的药物的一致递送的方法和制品。

    Osmotic Delivery System Flow Modulator Apparatus and Method
    2.
    发明申请
    Osmotic Delivery System Flow Modulator Apparatus and Method 审中-公开
    渗流输送系统流量调节装置及方法

    公开(公告)号：US20080071253A1

    公开(公告)日：2008-03-20

    申请号：US11856050

    申请日：2007-09-16

    申请人： Lewis Peterson ,  Fred Maruyama ,  Houdin Dehnad ,  Lawton Hom ,  Kevin Sly ,  Craig Davis ,  John Peery

    发明人： Lewis Peterson ,  Fred Maruyama ,  Houdin Dehnad ,  Lawton Hom ,  Kevin Sly ,  Craig Davis ,  John Peery

    IPC分类号： A61K9/22 ,  B21D51/16

    CPC分类号： A61M5/14276 ,  A61K9/0004 ,  A61M5/141 ,  A61M5/14526 ,  A61M5/16813 ,  Y10T29/494

    摘要： An osmotic delivery system flow modulator assembly, an osmotic delivery system with a flow modulator assembly, and a method of assembling an osmotic delivery system. The osmotic delivery system flow modular assembly includes a body having a hole located through the body and communicating two opposing ends of the body. The use of the osmotic delivery system flow modulator assembly lessens the chance that air or gas pockets will form in the enclosure of the osmotic delivery system during assembly of the system. Because less air is within the osmotic delivery system, performance of the system is enhanced. Use of the flow modulator assembly also lessens the chance that beneficial agent will be wasted during assembly of the osmotic delivery system.

    摘要翻译： 渗透递送系统流调节器组件，具有流量调节器组件的渗透递送系统以及组装渗透递送系统的方法。 渗透递送系统流模块化组件包括具有穿过本体并且连通主体的两个相对端的孔的主体。 渗透输送系统流量调节器组件的使用减少了在组装系统期间在渗透递送系统的外壳中形成空气或气体袋的机会。 由于渗透输送系统内的空气较少，因此能够提高系统的性能。 流动调节器组件的使用也减少了在渗透输送系统的组装期间有益剂将被浪费的机会。