公开(公告)号：US09233961B2

公开(公告)日：2016-01-12

申请号：US14209536

申请日：2014-03-13

申请人： Arnab Kumar Chatterjee ,  Fang Liang ,  Casey Jacob Nelson Mathison ,  Pranab Kumar Mishra ,  Valentina Molteni ,  Advait Suresh Nagle ,  Frantisek Supek ,  Liying Jocelyn Tan ,  Agnes Vidal ,  Michael Herman Gelb ,  Frederick Simmons Buckner ,  Hari Babu Tatipaka ,  Neil Richard Norcross ,  John Robert Gillespie

发明人： Arnab Kumar Chatterjee ,  Fang Liang ,  Casey Jacob Nelson Mathison ,  Pranab Kumar Mishra ,  Valentina Molteni ,  Advait Suresh Nagle ,  Frantisek Supek ,  Liying Jocelyn Tan ,  Agnes Vidal ,  Michael Herman Gelb ,  Frederick Simmons Buckner ,  Hari Babu Tatipaka ,  Neil Richard Norcross ,  John Robert Gillespie

IPC分类号： C07D471/02 ,  A61K31/50 ,  A61K31/415 ,  C07D473/00 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04

CPC分类号： C07D473/00 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04

摘要： The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a parasite, such as Leishmaniasis, Human African Trypanosomiasis and Chagas disease.

公开(公告)号：US20070025885A1

公开(公告)日：2007-02-01

申请号：US11381815

申请日：2006-05-05

申请人： Richard Bunch ,  Frederick Simmons ,  Edward Alderman

发明人： Richard Bunch ,  Frederick Simmons ,  Edward Alderman

IPC分类号： B01L3/00

CPC分类号： B01L3/5085 ,  B01L2200/025 ,  B01L2300/0829

摘要： A microtitre plate having a relieved perimeter includes a plate defining a plurality of wells and the perimeter of the plate is horizontally relieved. Alternatively, a microtitre plate may include a base and a holding section extending from the base. The holding section defines a plurality of wells and the perimeter thereof being horizontally relieved.

摘要翻译： 具有减轻周长的微量滴定板包括限定多个孔的板，并且板的周边被水平地释放。 或者，微量滴定板可以包括基部和从基部延伸的保持部。 保持部分限定多个井，并且其周边被水平地释放。

公开(公告)号：US20140275013A1

公开(公告)日：2014-09-18

申请号：US14209536

申请日：2014-03-13

申请人： Arnab Kumar CHATTERJEE ,  Fang LIANG ,  Casey Jacob Nelson MATHISON ,  Pranab Kumar MISHRA ,  Valentina MOLTENI ,  Advait Suresh Nagle ,  Frantisek SUPEK ,  Liying Jocelyn TAN ,  Agnes VIDAL ,  Michael Herman GELB ,  Frederick Simmons BUCKNER ,  Hari Babu TATIPAKA ,  Neil Richard NORCROSS ,  John Robert GILLESPIE

发明人： Arnab Kumar CHATTERJEE ,  Fang LIANG ,  Casey Jacob Nelson MATHISON ,  Pranab Kumar MISHRA ,  Valentina MOLTENI ,  Advait Suresh Nagle ,  Frantisek SUPEK ,  Liying Jocelyn TAN ,  Agnes VIDAL ,  Michael Herman GELB ,  Frederick Simmons BUCKNER ,  Hari Babu TATIPAKA ,  Neil Richard NORCROSS ,  John Robert GILLESPIE

IPC分类号： C07D473/00 ,  C07D471/04

CPC分类号： C07D473/00 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04

摘要： The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a parasite, such as Leishmaniasis, Human African Trypanosomiasis and Chagas disease.

公开(公告)号：US5517812A

公开(公告)日：1996-05-21

申请号：US342693

申请日：1994-11-21

申请人： Frederick Simmons

发明人： Frederick Simmons

IPC分类号： H01B13/26 ,  D02G3/36 ,  D02G3/06

CPC分类号： H01B13/26

摘要： A method and system are provided for automatically controlling tension of an armour tape being wrapped around a continuous strand of material, such as an electrical cable, travelling through an armouring machine having a reel of tape and tape feed rolls rotating around the strand and having a motor or suitable variable speed drive (such as a P.I.V. variable speed drive) for controlling the speed of rotation of the tape feed rolls and thus of tape feed rate. To achieve automatic control, the diameter of the strand entering the machine is measured, preferably by a laser, and the diameter of the armour over the strand exiting the machine is also measured, also preferably by a laser. The measurements are communicated to a computer which compares them to preset values. The computer drives the motor or variable speed drive and adjusts them when required depending on the measurements of the two diameters and so as to maintain the preset values during the wrapping operation.

摘要翻译： 提供了一种方法和系统，用于自动控制缠绕在连续的一束材料（例如电缆）周围的铠装带的张力，该电缆穿过具有绕线束旋转的带卷和带馈送辊的铠装机，并且具有 电机或适合的变速驱动器（例如PIV变速驱动器），用于控制送带辊的旋转速度，从而控制送带速度。 为了实现自动控制，优选地通过激光测量进入机器的线的直径，并且也优选地通过激光测量在离开机器的线束上的铠装的直径。 将测量值传送给将计算机与预设值进行比较的计算机。 计算机驱动电动机或变速驱动器，并根据两个直径的测量值进行调整，以便在包装操作期间保持预设值。