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    Methods for the detection and identification of crystals in biological fluids
    1.
    发明授权
    Methods for the detection and identification of crystals in biological fluids 失效
    检测和鉴定生物体液中晶体的方法

    公开(公告)号：US06413778B1

    公开(公告)日：2002-07-02

    申请号：US09235124

    申请日：1999-01-21

    申请人： Charles R. Carpenter ,  Melanie Tornberg ,  Genevieve Clark

    发明人： Charles R. Carpenter ,  Melanie Tornberg ,  Genevieve Clark

    IPC分类号： G01N3348

    CPC分类号： G01N33/493 ,  Y10T436/25375

    摘要： The present invention relates to devices, methods and kits for the detection and identification of crystals which may be present in a biological fluid, such as urine from a cat. The device may include a filter and an absorbent material. The fluid may be transferred onto the filter, and fluid passes through the filter and into the absorbent material, thereby isolating crystals on a surface of or within the structure of the filter or membrane. The crystals are then available for staining which will reveal a determining component of the crystals. The device may also include a member for inhibiting backflow from the absorbent material to the filter. The present invention also provides methods for detecting and identifying crystals which may be present in biological fluids. The methods include the steps of isolating the crystals on the surface of or within the structure of a filter or membrane, and contacting the crystals with an indicator which is specific for a determining component of the crystals type. Also provided are kits which include the devices of the present invention, and reagents and other materials necessary to conduct the methods of the present invention.

    摘要翻译： 本发明涉及用于检测和鉴定可能存在于生物流体例如来自猫的尿液中的晶体的装置，方法和试剂盒。 该装置可以包括过滤器和吸收材料。 流体可以转移到过滤器上，并且流体通过过滤器并进入吸收材料，从而在过滤器或膜的结构的表面上或内部分离晶体。 然后晶体可用于染色，其将显示晶体的确定组分。 该装置还可以包括用于抑制从吸收材料向过滤器回流的构件。本发明还提供了用于检测和鉴定可能存在于生物流体中的晶体的方法。 所述方法包括以下步骤：将过滤器或膜的结构表面上或结晶内的晶体分离，并将晶体与特定于晶体类型的确定组分的指示剂接触。还提供了包括装置的试剂盒 本发明的方法，以及进行本发明方法所需的试剂和其他材料。