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公开(公告)号:US4446064A
公开(公告)日:1984-05-01
申请号:US218075
申请日:1980-12-19
申请人: Joseph Larner , Kang Cheng , Gail Galasko
发明人: Joseph Larner , Kang Cheng , Gail Galasko
CPC分类号: A61K35/34 , Y10S530/841
摘要: An insulin mediator substance produced by the process comprising: contacting muscle tissue with insulin; deproteinizing the muscle tissue; removing the major nucleotides from the deproteinized muscle tissue; chromatographing the so-treated product on a Sephadex G-25 column using 0.05 N formic acid; and recovering the fraction wherein the major 230-nm absorbance peak corresponds with the ninhydrin-positive peak.
摘要翻译: 通过该方法产生的胰岛素介体物质包括:使肌肉组织与胰岛素接触; 去蛋白肌肉组织; 去除脱蛋白肌肉组织中的主要核苷酸; 使用0.05N甲酸在Sephadex G-25柱上色谱处理如此处理的产物; 并回收其中主要的230nm吸收峰对应于茚三酮正峰的级分。