公开(公告)号：US20060292182A1

公开(公告)日：2006-12-28

申请号：US11168243

申请日：2005-06-27

申请人： Lajos Kemeny ,  Zoltan Novak ,  Attila Dobozy ,  Zsolt Bor ,  Gavor Szabo ,  Bela Racz ,  Ferenc Ignacz

发明人： Lajos Kemeny ,  Zoltan Novak ,  Attila Dobozy ,  Zsolt Bor ,  Gavor Szabo ,  Bela Racz ,  Ferenc Ignacz

IPC分类号： A61K39/35

CPC分类号： A61N5/0603 ,  A61N2005/0661

摘要： A photoadjuvant immunotherapeutical method includes the steps of providing a phototherapeutical apparatus, comprising a light source, an optical guidance system, and a patient interface; determining a minimal erythema dose; performing phototherapy by irradiating a target surface with the phototherapeutical apparatus; and performing immunotherapy by exposing the irradiated target surface to an antigen. The method can be applied to treat allergic diseases, including allergic rhinitis, rhinoconjunctivitis, asthma, and atopic dermatitis, as well as to treat autoimmune diseases. UVA, UVB and visible light can be used, emitted from a quartz bulb with a small discharge volume. The phototherapy increases the tolerance of a patient's body toward an antigen. During immunotherapy the irradiated target surface can be exposed to a naturally present antigen or to an administered antigen. The method can be used to treat RSA by preventing rejection of the fotus, or to suppress rejection reactions in organ or cell transplantation.

摘要翻译： 光辅助免疫治疗方法包括提供包括光源，光引导系统和患者界面的光治疗装置的步骤; 确定最小的红斑剂量; 通过用光电设备照射目标表面进行光疗; 并通过将照射的靶表面暴露于抗原来进行免疫治疗。 该方法可用于治疗过敏性疾病，包括过敏性鼻炎，鼻结膜炎，哮喘和特应性皮炎，以及治疗自身免疫性疾病。 可以使用UVA，UVB和可见光，从具有小放电容积的石英灯泡发射。 光疗增加了患者身体对抗原的耐受性。 在免疫治疗期间，照射的靶表面可暴露于天然存在的抗原或被施用的抗原。 该方法可用于通过预防fotus的排斥或抑制器官​​或细胞移植排斥反应来治疗RSA。