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    Photoadjuvant immunotherapy
    1.
    发明申请
    Photoadjuvant immunotherapy 审中-公开
    光辅助免疫治疗

    公开(公告)号：US20060292182A1

    公开(公告)日：2006-12-28

    申请号：US11168243

    申请日：2005-06-27

    申请人： Lajos Kemeny ,  Zoltan Novak ,  Attila Dobozy ,  Zsolt Bor ,  Gavor Szabo ,  Bela Racz ,  Ferenc Ignacz

    发明人： Lajos Kemeny ,  Zoltan Novak ,  Attila Dobozy ,  Zsolt Bor ,  Gavor Szabo ,  Bela Racz ,  Ferenc Ignacz

    IPC分类号： A61K39/35

    CPC分类号： A61N5/0603 ,  A61N2005/0661

    摘要： A photoadjuvant immunotherapeutical method includes the steps of providing a phototherapeutical apparatus, comprising a light source, an optical guidance system, and a patient interface; determining a minimal erythema dose; performing phototherapy by irradiating a target surface with the phototherapeutical apparatus; and performing immunotherapy by exposing the irradiated target surface to an antigen. The method can be applied to treat allergic diseases, including allergic rhinitis, rhinoconjunctivitis, asthma, and atopic dermatitis, as well as to treat autoimmune diseases. UVA, UVB and visible light can be used, emitted from a quartz bulb with a small discharge volume. The phototherapy increases the tolerance of a patient's body toward an antigen. During immunotherapy the irradiated target surface can be exposed to a naturally present antigen or to an administered antigen. The method can be used to treat RSA by preventing rejection of the fotus, or to suppress rejection reactions in organ or cell transplantation.

    摘要翻译： 光辅助免疫治疗方法包括提供包括光源，光引导系统和患者界面的光治疗装置的步骤; 确定最小的红斑剂量; 通过用光电设备照射目标表面进行光疗; 并通过将照射的靶表面暴露于抗原来进行免疫治疗。 该方法可用于治疗过敏性疾病，包括过敏性鼻炎，鼻结膜炎，哮喘和特应性皮炎，以及治疗自身免疫性疾病。 可以使用UVA，UVB和可见光，从具有小放电容积的石英灯泡发射。 光疗增加了患者身体对抗原的耐受性。 在免疫治疗期间，照射的靶表面可暴露于天然存在的抗原或被施用的抗原。 该方法可用于通过预防fotus的排斥或抑制器官​​或细胞移植排斥反应来治疗RSA。

    Phototherapeutical method and system for the treatment of inflammatory and hyperproliferative disorders of the nasal mucosa
    2.
    发明申请
    Phototherapeutical method and system for the treatment of inflammatory and hyperproliferative disorders of the nasal mucosa 审中-公开
    用于治疗鼻粘膜炎症和过度增生性疾病的光疗法和系统

    公开(公告)号：US20060111760A1

    公开(公告)日：2006-05-25

    申请号：US11319684

    申请日：2005-12-28

    申请人： Lajos Kemeny ,  Zsolt Bor ,  Gabor Szabo ,  Ferenc Ignacz ,  Bela Racz ,  Attila Dobozy

    发明人： Lajos Kemeny ,  Zsolt Bor ,  Gabor Szabo ,  Ferenc Ignacz ,  Bela Racz ,  Attila Dobozy

    IPC分类号： A61N5/06

    CPC分类号： A61N5/0603 ,  A61N5/0601 ,  A61N5/062 ,  A61N2005/0605 ,  A61N2005/0606 ,  A61N2005/0607 ,  A61N2005/0608 ,  A61N2005/0609 ,  A61N2005/0611 ,  A61N2005/0644 ,  A61N2005/0661 ,  A61N2005/067

    摘要： A phototherapeutical apparatus is described, including a light source, generating high intensity visible light, in some embodiments in combination with ultraviolet light, an optical guidance system, and a patient interface. The patient interface can be insertable at least partially into a nasal cavity and is operable to apply the generated light to a tissue surface of the nasal cavity. Applying the apparatus includes providing the phototherapeutical apparatus, preparing for the application of the apparatus, inserting the patient interface into the nasal cavity, and applying the generated light by the patient interface to a tissue surface of the nasal cavity, wherein the tissue of the nasal cavity has an inflammatory or a hyperproliferative disease. The inflammatory diseases include rhinitis, sinusitis, and rhinosinusitis. A photodynamical therapy is also described, applying photosensitizing substances before the treatment with light. The phototherapeutical method is also effective for the prevention of inflammatory or hyperproliferative diseases.

    摘要翻译： 描述了一种光治疗装置，包括光源，在一些实施例中与紫外光，光学引导系统和患者接口相结合产生高强度可见光。 患者界面可以至少部分地插入到鼻腔中并且可操作以将产生的光施加到鼻腔的组织表面。 应用该设备包括提供光疗设备，准备应用该设备，将患者接口插入鼻腔，以及将由患者接口产生的光施加到鼻腔的组织表面，其中鼻腔的组织 空腔具有炎性或过度增生性疾病。 炎性疾病包括鼻炎，鼻窦炎和鼻鼻窦炎。 还描述了光动力疗法，在用光处理之前应用光敏物质。 光疗法对于预防炎性或过度增生性疾病也是有效的。

    Phototherapeutical apparatus and method for the treatment and prevention of diseases of body cavities
    4.
    发明申请
    Phototherapeutical apparatus and method for the treatment and prevention of diseases of body cavities 审中-公开
    用于治疗和预防体腔疾病的光疗法和方法

    公开(公告)号：US20060235492A1

    公开(公告)日：2006-10-19

    申请号：US11453736

    申请日：2006-06-15

    申请人： Lajos Kemeny ,  Zsolt Bor ,  Gabor Szabo ,  Ferenc Ignacz ,  Bela Racz ,  Attila Dobozy

    发明人： Lajos Kemeny ,  Zsolt Bor ,  Gabor Szabo ,  Ferenc Ignacz ,  Bela Racz ,  Attila Dobozy

    IPC分类号： A61N5/06

    CPC分类号： A61N5/0603 ,  A61N5/0601 ,  A61N5/062 ,  A61N2005/0605 ,  A61N2005/0606 ,  A61N2005/0607 ,  A61N2005/0608 ,  A61N2005/0609 ,  A61N2005/0611 ,  A61N2005/0644 ,  A61N2005/0661 ,  A61N2005/067

    摘要： A phototherapeutical apparatus and method are described. The apparatus includes an ultraviolet light source, an optical guidance system, and a patient interface. The patient interface is insertable at least partially into a body cavity and is operable to apply the guided ultraviolet light to a tissue surface of a body cavity. The method includes providing the phototherapeutical apparatus, preparing for the application of the phototherapeutical apparatus, inserting the patient interface at least partially into a body cavity, and applying the ultraviolet light by the patient interface to a tissue surface of a body cavity, wherein the tissue of the body cavity has an inflammatory or a hyperproliferative disease. The inflammatory diseases include rhinitis, sinusitis and rhinosinusitis. A photochemotherapeutical method is also described, using photosensitizing substances, such as psoralen before treatment with ultraviolet light. The phototherapeutical method is also effective for the prevention of inflammatory or hyperproliferative diseases.

    摘要翻译： 描述了光治疗装置和方法。 该装置包括紫外线光源，光学引导系统和患者接口。 患者界面至少部分地插入体腔内，并且可操作以将被引导的紫外线施加到体腔的组织表面。 该方法包括提供光疗设备，准备应用光疗设备，将患者界面至少部分地插入体腔，以及将患者界面的紫外线施加到体腔的组织表面，其中组织 的体腔具有炎性或过度增生性疾病。 炎性疾病包括鼻炎，鼻窦炎和鼻鼻窦炎。 还描述了使用光敏物质，例如用紫外线处理之前的补骨脂素的光化学治疗方法。 光疗法对于预防炎性或过度增生性疾病也是有效的。