公开(公告)号：US20050247307A1

公开(公告)日：2005-11-10

申请号：US11121031

申请日：2005-05-04

申请人： Geoffrey Maksym ,  Carolyn Lall

发明人： Geoffrey Maksym ,  Carolyn Lall

IPC分类号： A61B5/085 ,  A61B5/087 ,  A61M11/00 ,  A61M16/00 ,  G06F17/18 ,  G06F19/00

CPC分类号： A61B5/4884 ,  A61B5/085 ,  A61B5/087 ,  G06F19/00 ,  G06F19/3456

摘要： The invention relates to a method of assessing airway variability in airway responsiveness or asthma by measuring the variation of resistance (Rrs) by a forced oscillation technique utilizing either a single or a plurality of input frequencies during a plurality of respiratory cycles of a patient; calculating the statistical variability of the Rrs for the patient; and, correlating the statistical variability of the Rrs of the patient to a standard curve to quantify the degree of asthma of the patient. The invention also enables the effectiveness of a bronchoactive agent to be measured.

摘要翻译： 本发明涉及通过在患者的多个呼吸周期期间利用单个或多个输入频率的强制振荡技术来测量电阻变化（Rrs）来评估气道反应性或哮喘中气道变异性的方法。 计算患者Rrs的统计学变异性; 并且将患者的Rrs的统计变异性与标准曲线相关联，以量化患者的哮喘程度。 本发明还能够测量支气管活性剂的有效性。

公开(公告)号：US6074350A

公开(公告)日：2000-06-13

申请号：US47398

申请日：1998-02-25

申请人： Peter Tiffany Macklem ,  Christopher Kenyon ,  Anne Vezina ,  Geoffrey Maksym

发明人： Peter Tiffany Macklem ,  Christopher Kenyon ,  Anne Vezina ,  Geoffrey Maksym

IPC分类号： A61B5/085 ,  A61N5/00

CPC分类号： A61B5/085

摘要： The variation in flow resistance of the respiratory system (Rrs) is determined as an indicator of variations in airway calibre, by oscillating the system, for example at 6 Hz for 5-15 minutes and determining the variations in ratio of the pressure difference (Prs) across the system that is in phase with flow, to flow V. The variation in airway calibre may be employed as a prognostic indicator in asthmatics and also to assess the efficacy of treatment.

摘要翻译： 呼吸系统（Rrs）的流阻的变化被确定为气道口径变化的指标，通过使系统振荡，例如在6Hz下5-15分钟，并确定压力差的比值（Prs ）跨越与流相同步的系统，流向+ E，点V + EE。 气道口径的变化可用作哮喘患者的预后指标，也可用于评估治疗效果。