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公开(公告)号:US08702959B2
公开(公告)日:2014-04-22
申请号:US12981592
申请日:2010-12-30
申请人: Yosi Shacham-Diamand , Hadar Ben-Yoav , Shimshon Belkin , Rami Pedahzur , Alva Biran , Georg Reifferscheid , Sebastian Buchinger
发明人: Yosi Shacham-Diamand , Hadar Ben-Yoav , Shimshon Belkin , Rami Pedahzur , Alva Biran , Georg Reifferscheid , Sebastian Buchinger
CPC分类号: G01N27/403 , B33Y80/00 , Y10T29/49117
摘要: A system for analyzing a liquid is provided. The system comprises: an electrochemical unit having an electrochemical microchamber for receiving a sample of the liquid and electrochemically analyzing the sample; and a microfluidic unit being attached to the electrochemical unit and having microchannels constituted for sampling the sample in situ and feeding the sample to the electrochemical microchamber. Also provided are nucleic acid constructs and cells comprising same for analyte detection.
摘要翻译: 提供了用于分析液体的系统。 该系统包括:具有用于接收液体样品并电化学分析样品的电化学微室的电化学单元; 以及微流体单元,其连接到电化学单元并且具有构造用于原位取样和将样品送入电化学微室的微通道。 还提供了核酸构建体和包含用于分析物检测的细胞的细胞。
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公开(公告)号:US20110155587A1
公开(公告)日:2011-06-30
申请号:US12981592
申请日:2010-12-30
申请人: Yosi Shacham-Diamand , Hadar Ben-Yoav , Shimshon Belkin , Rami Pedahzur , Alva Biran , Georg Reifferscheid , Sebastian Buchinger
发明人: Yosi Shacham-Diamand , Hadar Ben-Yoav , Shimshon Belkin , Rami Pedahzur , Alva Biran , Georg Reifferscheid , Sebastian Buchinger
IPC分类号: G01N27/416 , G01N27/403 , G01N27/26 , H01R43/00 , C12N15/63 , C12N1/21
CPC分类号: G01N27/403 , B33Y80/00 , Y10T29/49117
摘要: A system for analyzing a liquid is provided. The system comprises: an electrochemical unit having an electrochemical microchamber for receiving a sample of the liquid and electrochemically analyzing the sample; and a microfluidic unit being attached to the electrochemical unit and having microchannels constituted for sampling the sample in situ and feeding the sample to the electrochemical microchamber. Also provided are nucleic acid constructs and cells comprising same for analyte detection.
摘要翻译: 提供了用于分析液体的系统。 该系统包括:具有用于接收液体样品并电化学分析样品的电化学微室的电化学单元; 以及微流体单元,其连接到电化学单元并且具有构造用于原位取样和将样品送入电化学微室的微通道。 还提供了核酸构建体和包含用于分析物检测的细胞的细胞。
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公开(公告)号:US20050070006A1
公开(公告)日:2005-03-31
申请号:US10482790
申请日:2002-06-25
IPC分类号: G01N33/53 , C12N1/21 , C12Q1/02 , C12Q1/68 , C12Q1/6883 , C12Q1/689 , G01N33/566
CPC分类号: C12Q1/689 , C12Q1/6883 , C12Q2600/142
摘要: The invention relates to a method and means for the rapid identification of mutations. The test strains used in the invention contain a reporter system and a selection marker. An antibiotic resistance protein which after mutation allows the selective growth of the revertant and the targeted induction of the inducible reporter system of the developing revertants acts as the selection marker. Proteins that are capable of directly or indirectly triggering a measuring signal are used as the reporters. The mutations are identified by means of the reporter signal of the developing revertants, in such a way that the evaluation can take place after only a few hours.
摘要翻译: 本发明涉及快速鉴定突变的方法和手段。 本发明中使用的测试菌株含有报道系统和选择标记。 突变后的抗生素抗性蛋白质允许回复体的选择性生长,并且靶向诱导发育中的反转体的诱导型报告系统作为选择标记物。 能够直接或间接触发测量信号的蛋白质被用作记者。 通过发展中的回复体的报道信号鉴定突变,使得评价仅在几小时后才能发生。
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