公开(公告)号：US20060161000A1

公开(公告)日：2006-07-20

申请号：US11314586

申请日：2005-12-21

Applicant: Martyn Poliakoff ,  Paul Hamley ,  Chong Yan ,  Eduardo Cepeda ,  Graham Aird ,  Alexander Coote ,  Ian Pearson ,  William Thomas

Inventor： Martyn Poliakoff ,  Paul Hamley ,  Chong Yan ,  Eduardo Cepeda ,  Graham Aird ,  Alexander Coote ,  Ian Pearson ,  William Thomas

IPC: C07D201/02

CPC classification number: C07D201/08

Abstract: A process for the manufacture of a lactam from an amino alkane nitrile and/or its hydrolysis derivatives, comprising reacting a solution comprising at least about 5% by weight amino alkane nitrile in water at a temperature of greater than or equal to about 350° C. and at a pressure of greater than about 250 bar. Optionally, a dilute acid may be added as a catalyst.

Abstract translation: 一种用于从氨基烷腈和/或其水解衍生物制备内酰胺的方法，包括使包含至少约5重量％氨基烷腈的溶液在大约或等于约350℃的温度下在水中反应 并且在大于约250巴的压力下。 任选地，可以加入稀酸作为催化剂。