公开(公告)号：US06479708B1

公开(公告)日：2002-11-12

申请号：US09442873

申请日：1999-11-18

申请人： Gunilla B. Jacobson ,  William Tumas ,  Keith P. Johnston

发明人： Gunilla B. Jacobson ,  William Tumas ,  Keith P. Johnston

IPC分类号： C07C4500

CPC分类号： C07C45/294 ,  C07B61/00 ,  C07C5/03 ,  C07C45/50 ,  C07C47/02

摘要： A process is provided for catalyzing an organic reaction to form a reaction product by placing reactants and a catalyst for the organic reaction, the catalyst of a metal complex and at least one ligand soluble within one of the phases of said aqueous biphasic system, within an aqueous biphasic system including a water phase, a dense phase fluid, and a surfactant adapted for forming an emulsion or microemulsion within the aqueous biphasic system, the reactants soluble within one of the phases of the aqueous biphasic system and convertible in the presence of the catalyst to a product having low solubility in the phase in which the catalyst is soluble; and, maintaining the aqueous biphasic system under pressures, at temperatures, and for a period of time sufficient for the organic reaction to occur and form the reaction product and to maintain sufficient density on the dense phase fluid, the reaction product characterized as having low solubility in the phase in which the catalyst is soluble.

摘要翻译： 提供了一种方法，用于催化有机反应以形成反应产物，将反应物和用于有机反应的催化剂，金属络合物的催化剂和至少一种可溶于所述水相双相体系的相之一的配体在一种 水相双相系统，包括水相，致密相流体和适于在水相双相体系内形成乳液或微乳液的表面活性剂，所述反应物可溶于水相双相体系的一相中并且在催化剂存在下可转化 涉及在催化剂可溶的相中具有低溶解度的产物; 并在保持水相双相系统的压力下，在足以使有机反应发生并形成反应产物并在密相流体上保持足够的密度的温度下持续一段时间，反应产物的特征在于溶解度低 在催化剂可溶的阶段。