公开(公告)号：US20180141947A1

公开(公告)日：2018-05-24

申请号：US15736510

申请日：2016-06-24

Applicant: Meredeth Ann MCGOWAN ,  Hua ZHOU ,  Jason D. KATZ ,  Lihu YANG ,  Joey L. METHOT ,  Kathryn Ann LIPFORD ,  Shimin XU ,  Ning FU ,  Guoquan XU ,  Deqian BIAN ,  Jianmin FU ,  Yabin LI ,  kin Chiu FONG ,  MERCK SHARP & DOHME CORP.

Inventor： Meredith Ann McGowan ,  Hua Zhou ,  Jason D. Katz ,  Lihu Yang ,  Joey L. Methot ,  Kathryn Ann Lipford ,  Shimin Xu ,  Ning Fu ,  Guoquan Xu ,  Deqian Bian ,  Jianmin Fu ,  Yabin Li ,  Kin Chiu Fong

IPC: C07D473/30 ,  C07D473/34 ,  C07D519/00 ,  C07D471/04 ,  A61P35/00 ,  A61P19/02 ,  A61P11/06 ,  A61P11/00 ,  A61P37/00 ,  A61P17/06 ,  A61P11/08

CPC classification number: C07D473/30 ,  A61K45/06 ,  A61P11/00 ,  A61P11/06 ,  A61P11/08 ,  A61P17/06 ,  A61P19/02 ,  A61P35/00 ,  A61P37/00 ,  C07D471/04 ,  C07D473/34 ,  C07D519/00

Abstract: The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.