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公开(公告)号:US11958664B2
公开(公告)日:2024-04-16
申请号:US17775079
申请日:2020-11-04
Applicant: Horus Pharma , Santen SA
Inventor: Renzo Este
CPC classification number: B65D47/205 , B65D47/18 , B65D47/2056 , B65D2547/06
Abstract: The invention relates to a dispensing device for dispensing a fluid product. The device includes a dispensing end; an attachment end; and a dispensing valve provided between the attachment end and the dispensing end and formed by a flexible member and a rigid member. The dispensing valve is actuatable between an open position in which a dispensing channel is formed between the flexible member and the rigid member, and a closed position in which the dispensing channel is closed. The dispensing valve includes a first valve portion and a second valve portion. The second valve portion is located closer to the dispensing end than the first valve portion. The dispensing valve is configured such that a greater biasing force is applied onto the rigid member by the flexible member in the first valve portion than in the second valve portion when the dispensing valve is in the closed position.
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公开(公告)号:US11365031B2
公开(公告)日:2022-06-21
申请号:US17053508
申请日:2019-05-07
Applicant: Horus Pharma , Santen SA
Inventor: Jacques Pozzi
Abstract: The device for packaging and dispensing a product comprises a container (1) intended to contain in a sterile manner the product to be packaged and dispensed in the form of calibrated doses or drops by means of a dispensing accessory equipped with a mouthpiece (4) of the type having a flexible part (5), said accessory forming a dosing chamber (7) for the dispensing of the calibrated drop. An outer wall (8) of the mouthpiece delimits a space (18) equipped with one or more openings (19), the end of said mouthpiece (4) including a central channel (13) allowing the dispensing of the calibrated drop, associated with one or more lateral channels (11) leading into the space (18). A cover (14) equipped with an inner skirt (15), in the mounted state, creates an overpressure so as to eliminate any residual drop (10) which can subsist in the mouthpiece (4) at the end. Application to the dispensing of doses of sterile products, particularly of drops in ophthalmology.
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公开(公告)号:US20210221575A1
公开(公告)日:2021-07-22
申请号:US17053508
申请日:2019-05-07
Applicant: Horus Pharma , Santen SA
Inventor: Jacques Pozzi
Abstract: The device for packaging and dispensing a product comprises a container (1) intended to contain in a sterile manner the product to be packaged and dispensed in the form of calibrated doses or drops by means of a dispensing accessory equipped with a mouthpiece (4) of the type having a flexible part (5), said accessory forming a dosing chamber (7) for the dispensing of the calibrated drop. An outer wall (8) of the mouthpiece delimits a space (18) equipped with one or more openings (19), the end of said mouthpiece (4) including a central channel (13) allowing the dispensing of the calibrated drop, associated with one or more lateral channels (11) leading into the space (18). A cover (14) equipped with an inner skirt (15), in the mounted state, creates an overpressure so as to eliminate any residual drop (10) which can subsist in the mouthpiece (4) at the end. Application to the dispensing of doses of sterile products, particularly of drops in ophthalmology.
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公开(公告)号:US10993835B2
公开(公告)日:2021-05-04
申请号:US16033426
申请日:2018-07-12
Applicant: Horus Pharma
Inventor: Martine Claret , Pierre Roy
Abstract: Device for packaging and dispensing drops of a substance for ophthalmic use, generally fluid, semi-fluid or in suspension, emulsion or oily solution including a dispensing accessory with a first valve made of an elastomer material that allows the substance to pass through when the dispensing accessory is stressed, without allowing outside air to pass through in the opposite direction when the dispensing accessory is relaxed, characterized in that the first valve is covered by a layer of Parylene.
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公开(公告)号:US20210070510A1
公开(公告)日:2021-03-11
申请号:US17053226
申请日:2019-05-07
Applicant: Horus Pharma , Santen SA
Inventor: Jacques Pozzi
Abstract: The device (100) for packaging and dispensing a product, liquid or in gel form, optionally for an ophthalmic application, comprises a container (1) containing the product to be dispensed by a dispensing head (7), as well as a refilling and filtering assembly for the air entering the container (1) after a dispensing, the dispensing head delimiting one or more dosing chambers (5) and including at its end a flexible part (7) which can be actuated to allow the release of the dose of product in a compressed state of said chamber (5). The air refilling and filtering assembly has a sterilizing filter (11) which cooperates with a check valve (12), this assembly (11, 12) being typically located in a central or inner portion of the head (7). The supply of outside air is accomplished by means of a channel (16) leading to an outer orifice (10) able to be obturated by a cover (15).
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公开(公告)号:US11820546B2
公开(公告)日:2023-11-21
申请号:US17554335
申请日:2021-12-17
Applicant: Horus Pharma , Santen SA
Inventor: Jacques Pozzi
CPC classification number: B65D47/18 , B65D47/32 , A61F9/0008 , B05B11/007 , B65D47/2031
Abstract: The device (100) for packaging and dispensing a product, liquid or in gel form, optionally for an ophthalmic application, comprises a container (1) containing the product to be dispensed by a dispensing head (7), as well as a refilling and filtering assembly for the air entering the container (1) after a dispensing, the dispensing head delimiting one or more dosing chambers (5) and including at its end a flexible part (7) which can be actuated to allow the release of the dose of product in a compressed state of said chamber (5). The air refilling and filtering assembly has a sterilizing filter (11) which cooperates with a check valve (12), this assembly (11, 12) being typically located in a central or inner portion of the head (7). The supply of outside air is accomplished by means of a channel (16) leading to an outer orifice (10) able to be obturated by a cover (15).
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公开(公告)号:US20220388738A1
公开(公告)日:2022-12-08
申请号:US17775079
申请日:2020-11-04
Applicant: Horus Pharma , Santen SA
Inventor: Renzo Este , Caroline Chatard-Baptiste
Abstract: The device includes a dispensing end; an attachment end; and a dispensing valve provided between the attachment end and the dispensing end and formed by a flexible member and a rigid member. The dispensing valve is actuatable between an open position in which a dispensing channel is formed between the flexible member and the rigid member, and a closed position in which the dispensing channel is closed. The dispensing valve includes a first valve portion and a second valve portion. The second valve portion is located closer to the dispensing end than the first valve portion. The dispensing valve is configured such that a greater biasing force is applied onto the rigid member by the flexible member in the first valve portion than in the second valve portion when the dispensing valve is in the closed position.
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公开(公告)号:US20190307789A1
公开(公告)日:2019-10-10
申请号:US16439804
申请日:2019-06-13
Applicant: Horus Pharma
Inventor: Jean-François Rouland , Martine Claret , Claude Claret
IPC: A61K31/728 , A61K47/38 , A61K9/00 , A61K9/08 , A61K47/02
Abstract: The invention relates to a novel hyperosmolar composition of hyaluronic acid for the use thereof in the treatment of conical oedema.
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公开(公告)号:US10022266B2
公开(公告)日:2018-07-17
申请号:US14377241
申请日:2013-02-08
Applicant: Horus Pharma
Inventor: Martine Claret , Pierre Roy
Abstract: Device for packaging and dispensing drops of a substance for ophthalmic use, generally fluid, semi-fluid or in suspension, emulsion or oily solution, including a dispensing accessory with a first valve made of an elastomer material that allows the substance to pass through when the dispensing accessory is stressed, without allowing outside air to pass through in the opposite direction when the dispensing accessory is relaxed, characterized in that the first valve is covered by a layer of Parylene.
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公开(公告)号:US20240131543A1
公开(公告)日:2024-04-25
申请号:US18547561
申请日:2022-03-04
Applicant: HORUS PHARMA
Inventor: Oliver LALLEMENT , Este RENZO
CPC classification number: B05B11/0032 , B65D51/1611
Abstract: The present invention relates to a device comprising: —a container (1) intended to contain a product to be dispensed, —a cap (4), —a head mounted on the container and comprising: o a nozzle (31) for discharging the product, and o a collar (2) including: # an upper working portion intended to engage with the cap to close the distribution device, and # a lower combining portion intended to engage with the container, characterised in that the device further comprises at least one ventilation opening which opens onto the interface between the upper working portion and the lower combining portion so as to maintain an air communication channel between the outside and inside of the packaging device when the cap is mounted on the collar.
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