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公开(公告)号:US5674979A
公开(公告)日:1997-10-07
申请号:US584579
申请日:1996-01-11
申请人: Wolfgang Schramm , Hans J. Schramm
发明人: Wolfgang Schramm , Hans J. Schramm
CPC分类号: C07K14/005 , C07K14/8142 , C07K5/101 , C12N2740/16222
摘要: The invention relates to substances for the inhibition of symmetric proteins, in particular enzymes, in particular the inhibition of HIV protease, in the form of structurally symmetric or near symmetric enzyme inhibitors, chazacterized by the same symmetry, or approximate or piecewise (yet sufficient for inhibition) symmetry, as the enzyme molecule to be inhibited.
摘要翻译: 本发明涉及以结构对称或近似对称的酶抑制剂的形式抑制对称蛋白质,特别是酶,特别是抑制HIV蛋白酶的物质,其具有相同的对称性或近似或分段的(也足以用于 抑制)对称,作为待分解的酶分子。