Method based on bismuth ion for the treatment and prevention of a disease caused by a Shiga toxin
    1.
    发明授权
    Method based on bismuth ion for the treatment and prevention of a disease caused by a Shiga toxin 有权
    基于铋离子治疗和预防志贺毒素引起的疾病的方法

    公开(公告)号:US09468653B2

    公开(公告)日:2016-10-18

    申请号:US13503818

    申请日:2011-10-10

    摘要: The present invention relates to the a bismuth-based composition, particularly involving the use of bismuth ions, particularly the Bi+3 ion, for prevention and/or treatment of the haemolytic uremic syndrome, with the invention also relating to the use of a bismuth ion in the manufacture of a medicament for the prevention and/or treatment of an infection caused by a Shiga-toxin producing Escherichia coli strain, as well as to a method for preventing and/or treating the haemolytic uremic syndrome comprising administering bismuth ions to a patient in need thereof, and a method for inhibiting dissemination of the gene encoding virulence factors of a Shiga-toxin producing Escherichia coli strain in animals and humans.

    摘要翻译: 本发明涉及一种铋基组合物,特别涉及使用铋离子,特别是Bi + 3离子来预防和/或治疗溶血性尿毒症综合征,本发明还涉及使用铋 制备用于预防和/或治疗由产志贺毒素产生的大肠杆菌菌株引起的感染的药物的方法,以及用于预防和/或治疗溶血性尿毒综合征的方法,其包括将铋离子施用于 需要的患者,以及用于抑制编码在动物和人类中产生志贺毒素的大肠杆菌菌株的毒力因子的编码基因的扩散的方法。

    METHOD BASED ON BISMUTH ION FOR THE TREATMENT AND PREVENTION OF A DISEASE CAUSED BY A SHIGA TOXIN
    2.
    发明申请
    METHOD BASED ON BISMUTH ION FOR THE TREATMENT AND PREVENTION OF A DISEASE CAUSED BY A SHIGA TOXIN 有权
    用于治疗和预防由SHIGA毒素引起的疾病的双因子方法

    公开(公告)号:US20140205682A1

    公开(公告)日:2014-07-24

    申请号:US13503818

    申请日:2011-10-10

    摘要: The present invention relates to the a bismuth-based composition, particularly involving the use of bismuth ions, particularly the Bi+3 ion, for prevention and/or treatment of the haemolytic uremic syndrome, with the invention also relating to the use of a bismuth ion in the manufacture of a medicament for the prevention and/or treatment of an infection caused by a Shiga-toxin producing Escherichia coli strain, as well as to a method for preventing and/or treating the haemolytic uremic syndrome comprising administering bismuth ions to a patient in need thereof, and a method for inhibiting dissemination of the gene encoding virulence factors of a Shiga-toxin producing Escherichia coli strain in animals and humans.

    摘要翻译: 本发明涉及一种铋基组合物,特别涉及使用铋离子,特别是Bi + 3离子来预防和/或治疗溶血性尿毒症综合征,本发明还涉及使用铋 制备用于预防和/或治疗由产志贺毒素产生的大肠杆菌菌株引起的感染的药物的方法,以及用于预防和/或治疗溶血性尿毒综合征的方法,其包括将铋离子施用于 需要的患者,以及用于抑制编码在动物和人类中产生志贺毒素的大肠杆菌菌株的毒力因子的编码基因的扩散的方法。