公开(公告)号：US4945181A

公开(公告)日：1990-07-31

申请号：US936173

申请日：1986-12-01

申请人： Helmut Dick ,  Wolf-Dietrich Gradel ,  Mathias Weber

发明人： Helmut Dick ,  Wolf-Dietrich Gradel ,  Mathias Weber

IPC分类号： C07B57/00 ,  A61K31/10 ,  A61K31/165 ,  A61P31/04 ,  C07B31/00 ,  C07C67/00 ,  C07C313/00 ,  C07C315/04 ,  C07C317/32

CPC分类号： C07C315/04

摘要： The present invention provides a process for the preparation of thamphenicol (I) from D,L-threo-1-(p-methylsulphonylphenyl)-2-aminopropane-1, 3-diol hydrochloride (V) and intermediates thereof. The process comprises conversion to a corresponding benzal compound followed by hydrolysis to D,L-threo-aminodiol.HCl and the following steps: ##STR1##

摘要翻译： 本发明提供了从D，L-苏 - 1-（对甲基磺酰基苯基）-2-氨基丙烷-1,3-二醇盐酸盐（V）及其中间体制备苯乙烯酚（I）的方法。 该方法包括转化成相应的苯甲醛化合物，然后水解成D，L-苏氨基二氢-2H-氯化物，然后进行以下步骤：（1）图像（VI） ）硫霉素

公开(公告)号：US5104261A

公开(公告)日：1992-04-14

申请号：US615467

申请日：1990-11-19

申请人： Olov Anderson ,  Helmut Dick ,  Sverker Hartwig

发明人： Olov Anderson ,  Helmut Dick ,  Sverker Hartwig

IPC分类号： E21D9/00 ,  E21D9/087 ,  E21D9/11

CPC分类号： E21D9/11

摘要： Tunnel boring machine for reaming of a pilot tunnel (11). The machine housing (12) is provided with a projecting part in front of the boring head (13), said projecting part comprising a part (20) being fixed relative to the machine housing and a shield (19) being separable from the fixed part.This arrangement permits substantially uninterrupted excavation of the tunnel and prevents the excavated soil from becoming wedged between the boring head and the tunnel front.

公开(公告)号：US4232905A

公开(公告)日：1980-11-11

申请号：US25549

申请日：1979-03-30

申请人： Helmut Dick

发明人： Helmut Dick

IPC分类号： E21D9/10 ,  E21D9/11

CPC分类号： E21D9/104 ,  E21D9/117

摘要： A tunnelling machine has a swing unit (31) that is swingable about a horizontal axis (I). The swing unit has a head (50) that rotates about an axis (II) that is transverse to said horizontal axis and passes the horizontal at a distance below the horizontal axis. The head is equipped with a plurality of disc-cutters (53-58, 63) that are arranged to have their cutting edges on an imaginary sphere with a radius of about the same length as the swing radius. Upon simultaneous upward swinging of the swing unit and rotation of the head, the cutters cut both when on the leading side of the head and when on the trailing side. No cutting occurs during the return swing stroke. When the swing unit has been returned, the machine is advanced a step which is somewhat larger than the distance between the two axes, and another upward cutting stroke can be effected.

摘要翻译： 隧道机具有围绕水平轴线（I）摆动的摆动单元（31）。 摆动单元具有围绕横向于所述水平轴线的轴线（II）旋转的头部（50），并且在水平轴线之下的距离处穿过水平面。 头部配备有多个盘形切割器（53-58,63），其被设置成将其切割边缘设置在具有与摆动半径大致相同长度的半径的假想球体上。 当摆动单元同时向上摆动和头部旋转时，切割器在头部的前侧和当在后侧时都切割。 在返回摆动行程期间不会发生切割。 当摆动单元已经返回时，机器前进一个比两个轴之间的距离稍大的台阶，并且可以进行另一个向上的切割行程。