公开(公告)号：US5231189A

公开(公告)日：1993-07-27

申请号：US834328

申请日：1992-02-20

申请人： Hideaki Tuneki ,  Hitoshi Yano ,  Yuuji Shimasaki ,  Kimio Ariyoshi ,  Hideki Masada ,  Michio Ueshima

发明人： Hideaki Tuneki ,  Hitoshi Yano ,  Yuuji Shimasaki ,  Kimio Ariyoshi ,  Hideki Masada ,  Michio Ueshima

IPC分类号： B01J23/02 ,  B01J27/18 ,  C07D203/02 ,  C07D203/08 ,  C07D203/10 ,  C07D203/12 ,  C07D203/14

CPC分类号： C07D203/08 ,  B01J23/02 ,  B01J27/18 ,  B01J27/1806 ,  C07D203/02 ,  C07D203/10 ,  C07D203/12 ,  C07D203/14

摘要： The present invention provides a novel process for producing an N-substituted aziridine compound by subjecting an N-substituted alkanolamine to a gas-phase catalytic dehydration reaction (the following reaction formula). ##STR1## In the above formula, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each independently one member of selected from a hydrogen atom and alkyl groups of 1-4 carbon atoms, and X is one member selected from alkyl groups of 1-4 carbon atoms, a cyclohexyl group, a phenyl group, a benzyl group, hydroxyalkyl groups of 1-4 carbon atoms and aminoalkyl groups of 1-4 carbon atoms.Preferably, the N-substituted aziridine compound is produced at a high yield by subjecting an N-substituted alkanolamine to a gas-phase catalytic dehydration reaction in the presence of a silicon-containing or phosphorus-containing catalyst under the conditions of reaction pressure=5-250 mmHg, reaction temperature=300.degree.-450.degree. C. and space velocity=50-500 hr.sup.-1 (STP).