Insulin resistance improving agent
    4.
    发明申请
    Insulin resistance improving agent 审中-公开
    胰岛素抵抗改善剂

    公开(公告)号:US20060199761A1

    公开(公告)日:2006-09-07

    申请号:US10502051

    申请日:2002-07-26

    IPC分类号: A61K38/17 A61K48/00

    CPC分类号: A61K38/2264

    摘要: The invention provides an insulin resistance improving agent which contains, as an active component, a C-terminal globular domain of adiponectin, adiponectin, or a gene for the domain or adiponectin. The invention also provides a therapeutic agent for type 2 diabetes, which contains, as an active component, a C-terminal globular domain of adiponectin, adiponectin, or a gene for the domain or adiponectin. The invention reverses insulin resistance induced from a high fat diet and associated with obesity, and therefore, enables treatment of type 2 diabetes, which is the most common among other types of diabetes.

    摘要翻译: 本发明提供一种胰岛素抵抗性改善剂,其包含作为活性成分的脂联素的C末端球状结构域,脂联素或所述结构域或脂联素的基因。 本发明还提供了用于2型糖尿病的治疗剂,其包含作为活性成分的脂联素的C末端球状结构域,脂联素或所述结构域或脂联素的基因。 本发明逆转高脂肪饮食诱发的胰岛素抵抗并与肥胖相关,因此能够治疗其它类型糖尿病中最常见的2型糖尿病。