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1.发明公开公开(公告)号：US20240058408A1
公开(公告)日：2024-02-22
申请号：US18270687
申请日：2021-12-14
发明人： Sang Jun LEE , Se Young CHUNG
IPC分类号： A61K36/258 , A61K31/704 , A61P27/02
CPC分类号： A61K36/258 , A61K31/704 , A61P27/02 , A61K2236/331
摘要： A method for preventing or treating a macular degeneration disease, comprising administering a composition comprising a ginseng berry extract to a subject in need thereof. Since the composition can inhibit AE2 accumulation in retinal pigment epithelial cells, inhibit photooxidation, and inhibit outer nuclear layer damage of visual cells, it can be usefully used in preventing or treating macular degeneration disease.
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公开(公告)号：US11612629B2
公开(公告)日：2023-03-28
申请号：US17269514
申请日：2019-07-19
发明人： Woo Chang Jung , Sang Jun Lee , Se Young Jung
IPC分类号： A61K36/00 , A61K36/258 , A61P21/00
摘要： The present invention relates to a pharmaceutical composition for the prevention or treatment of muscle disease comprising a Panax ginseng berry extract as an active ingredient. The composition of the present invention alleviates the decrease in muscle weight and muscle fiber cross-sectional area caused by muscle atrophy, and reduces the increase in expression of MuRF-1 (Muscle RING-finger protein-1) and atrogin-1, which are involved in proteolysis of muscle proteins, so that it can be effectively used to prevent, ameliorate or treat muscle disease.
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公开(公告)号：US20210213085A1
公开(公告)日：2021-07-15
申请号：US17269514
申请日：2019-07-19
发明人： Woo Chang JUNG , Sang Jun LEE , Se Young JUNG
IPC分类号： A61K36/258 , A61P21/00
摘要： The present invention relates to a pharmaceutical composition for the prevention or treatment of muscle disease comprising a Panax ginseng berry extract as an active ingredient. The composition of the present invention alleviates the decrease in muscle weight and muscle fiber cross-sectional area caused by muscle atrophy, and reduces the increase in expression of MuRF-1 (Muscle RING-finger protein-1) and atrogin-1, which are involved in proteolysis of muscle proteins, so that it can be effectively used to prevent, ameliorate or treat muscle disease.
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