公开(公告)号：US20090088450A1

公开(公告)日：2009-04-02

申请号：US11658923

申请日：2005-08-18

申请人： Antoni Torrens Jover ,  Josep Mas Prio ,  Susana Yenes Minguez ,  Monica Garcia Lopez ,  Albert Dordal Zueras ,  Lus Romero Alonso ,  Hulmut Henrich Buschmann

发明人： Antoni Torrens Jover ,  Josep Mas Prio ,  Susana Yenes Minguez ,  Monica Garcia Lopez ,  Albert Dordal Zueras ,  Lus Romero Alonso ,  Hulmut Henrich Buschmann

IPC分类号： A61K31/472 ,  C07D217/18

CPC分类号： C07D513/04 ,  C07D217/04 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D409/14 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12

摘要： The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline propyl sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.

摘要翻译： 本发明涉及对5-HT 7受体具有药理活性的化合物，更具体地说，涉及一些四氢异喹啉丙磺酰胺化合物，其制备方法，包含它们的药物组合物及其用于治疗和/或预防 涉及5-HT的疾病，如CNS疾病。