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1.发明申请Pharmaceutical Composition For Preventintion And Treatment Of Restenosis Comprising Isoxazole Derivatives 有权用于预防和治疗包括异恶唑衍生物的再狭窄的药物组合物公开(公告)号：US20110028506A1
公开(公告)日：2011-02-03
申请号：US12666785
申请日：2008-06-30
Applicant: Sun Gwan Hwang , Sang Rak Choi , Jeong Woo Cho , Sung Jin Bae , Tae Sung Koo , So Young Lee , Kyung Chul Cho , Hyeon Cheol Gwon
Inventor： Sun Gwan Hwang , Sang Rak Choi , Jeong Woo Cho , Sung Jin Bae , Tae Sung Koo , So Young Lee , Kyung Chul Cho , Hyeon Cheol Gwon
IPC: A61K31/436 , C07D405/14 , C07D413/12 , C07D409/14 , A61K31/422 , A61K31/4439 , A61P9/10 , A61P9/08
CPC classification number: C07D413/14 , C07D413/12
Abstract: There is provided a pharmaceutical composition for prevention and treatment of restenosis comprising isoxazole derivatives. The pharmaceutical composition includes a therapeutic effective amount of isoxazole derivatives represented by Formula 1 or pharmaceutically available salts thereof. The pharmaceutical composition may be useful to prevent and treat vascular restenosis since the pharmaceutical composition shows an anti-restenosis activity and accelerates the re-endothelization.
Abstract translation: 提供了用于预防和治疗包含异恶唑衍生物的再狭窄的药物组合物。 药物组合物包含治疗有效量的由式1表示的异恶唑衍生物或其药学上可用的盐。 药物组合物可用于预防和治疗血管再狭窄，因为药物组合物显示出抗再狭窄活性并加速再内皮化。
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2.发明授权Pharmaceutical composition for prevention and treatment of restenosis comprising isoxazole derivatives 有权用于预防和治疗包括异恶唑衍生物的再狭窄的药物组合物公开(公告)号：US08518978B2
公开(公告)日：2013-08-27
申请号：US12666785
申请日：2008-06-30
Applicant: Sun Gwan Hwang , Sang Rak Choi , Jeong Woo Cho , Sung Jin Bae , Tae Sung Koo , So Young Lee , Kyung Chul Cho , Hyeon Cheol Gwon
Inventor： Sun Gwan Hwang , Sang Rak Choi , Jeong Woo Cho , Sung Jin Bae , Tae Sung Koo , So Young Lee , Kyung Chul Cho , Hyeon Cheol Gwon
CPC classification number: C07D413/14 , C07D413/12
Abstract: There is provided a pharmaceutical composition for prevention and treatment of restenosis comprising isoxazole derivatives. The pharmaceutical composition includes a therapeutic effective amount of isoxazole derivatives represented by Formula 1 or pharmaceutically available salts thereof. The pharmaceutical composition may be useful to prevent and treat vascular restenosis since the pharmaceutical composition shows an anti-restenosis activity and accelerates the re-endothelization.
Abstract translation: 提供了用于预防和治疗包含异恶唑衍生物的再狭窄的药物组合物。 药物组合物包含治疗有效量的由式1表示的异恶唑衍生物或其药学上可用的盐。 药物组合物可用于预防和治疗血管再狭窄，因为药物组合物显示出抗再狭窄活性并加速再内皮化。
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