PROCESS FOR PREPARING 17&agr;-ACETOXY-11&bgr;-[4-N,N(DIMETHYLAMINO)PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIENE-3,20-DIONE, INTERMEDIATES USEFUL IN THE PROCESS , AND PROCESSES FOR PREPARING SUCH INTERMEDIATES
    2.
    发明授权
    PROCESS FOR PREPARING 17&agr;-ACETOXY-11&bgr;-[4-N,N(DIMETHYLAMINO)PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIENE-3,20-DIONE, INTERMEDIATES USEFUL IN THE PROCESS , AND PROCESSES FOR PREPARING SUCH INTERMEDIATES 有权
    制备17α-乙酰氧基-11β-[4-N,N(二甲基氨基)苯基] -2-甲氧基-19-壬基-4,9-二烯-3,20-二酮的方法,该方法中有用的中间体和方法 准备这样的中间人

    公开(公告)号:US06768014B2

    公开(公告)日:2004-07-27

    申请号:US10169139

    申请日:2002-06-27

    IPC分类号: C07J500

    摘要: A compound having general formula (I) in which R1 is a member selected from the group consisting of —OCH3, —SCH3, —N(CH3)2, —NHCH3, —CHO, —COCH3 and —CHOHCH3; R2 is a member selected from the group consisting of halogen, alkyl, acyl, hydroxy, alkoxy, acyloxy, alkyl carbonate, cypionyloxy, S-alkyl and S-acyl; R3 is a member selected from the group consisting of alkyl, hydroxy, alkoxy and acyloxy; R4 is a member selected from the group consisting of hydrogen and alkyl; and X is a member selected from the group consisting of —O and —N—OR5, wherein R5 is a member selected from the group consisting of hydrogen and alkyl. In addition to providing the compounds of formula (I), the present invention provides methods wherein the compounds of formula (I) are advantageously used, inter alia, to antagonize endogenous progesterone; to induce menses; to treat endometriosis; to treat dysmenorrhea; to treat endocrine hormone-dependent tumors; to treat uterine fibroids; to inhibit uterine endometrial proliferation; to induce labor; and for contraception.

    摘要翻译: 具有通式(I)的化合物,其中R 1是选自-OCH 3,-SCH 3,-N(CH 3)2,-NHCH 3,-CHO,-COCH 3和-CHOHCH 3的成员; R 2是选自卤素,烷基,酰基,羟基,烷氧基,酰氧基,碳酸烷基酯,Cypion氧基,S-烷基和S-酰基的成员。 R 3是选自烷基,羟基,烷氧基和酰氧基的成员; R 4是选自氢和烷基的成员; 并且X是选自-O和-N-OR 5的成员,其中R 5是选自氢和烷基的成员。 除了提供式(I)化合物外,本发明提供了其中式(I)化合物有利地用于拮抗内源性孕酮的方法; 诱发月经; 治疗子宫内膜异位症; 治疗痛经; 治疗内分泌激素依赖性肿瘤; 治疗子宫肌瘤; 抑制子宫内膜增生; 诱导劳动; 和避孕。

    DATA STORAGE DEVICE AND METHOD FOR REDUCING FIRMWARE UPDATE TIME AND DATA PROCESSING SYSTEM INCLUDING THE DEVICE
    3.
    发明申请
    DATA STORAGE DEVICE AND METHOD FOR REDUCING FIRMWARE UPDATE TIME AND DATA PROCESSING SYSTEM INCLUDING THE DEVICE 有权
    用于减少固件更新时间的数据存储设备和方法以及包括设备的数据处理系统

    公开(公告)号:US20160124740A1

    公开(公告)日:2016-05-05

    申请号:US14865415

    申请日:2015-09-25

    IPC分类号: G06F9/445

    CPC分类号: G06F8/65 G06F8/63 G06F8/654

    摘要: A data storage device for reducing a firmware update time includes a non-volatile memory configured to store a firmware update image which will replace a current firmware image, a first volatile memory, and a processor configured to control an operation of the non-volatile memory and an operation of the first volatile memory. When a first code included in the current firmware image is executed by the processor, the first code generates data necessary for an operation of the data storage device and stores the data in the first volatile memory. When a second code included in the firmware update image is executed by the first code, the second code accesses and uses the data that has been stored in the first volatile memory.

    摘要翻译: 用于减少固件更新时间的数据存储装置包括被配置为存储将替换当前固件图像的固件更新图像的第一非易失性存储器,第一易失性存储器和被配置为控制非易失性存储器的操作的处理器 以及第一易失性存储器的操作。 当由处理器执行包括在当前固件图像中的第一代码时,第一代码产生数据存储设备的操作所需的数据,并将数据存储在第一易失性存储器中。 当通过第一代码执行包括在固件更新图像中的第二代码时,第二代码访问并使用已经存储在第一易失性存储器中的数据。