公开(公告)号：US09987327B2

公开(公告)日：2018-06-05

申请号：US15295281

申请日：2016-10-17

申请人： INSERM (INSTITUT NATIONAL DE LA SANTE ET DE EA RECHERCHE MEDICALE) ,  UNIVERSITE DE MONTPELLIER ,  ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS ,  UNIVERSITE PARIS EST CRETEIL VAL DE MARNE ,  UNIVERSITE D'ANGERS

发明人： Alain Lacampagne ,  Jerome Thireau ,  Olivier Cazorla ,  Jean-Yves Le Guennec ,  Jeremy Fauconnier ,  Maria del Carmen Martinez ,  Ramaroson Andriantsitohaina ,  Bijan Ghaleh-Marzban ,  Raffaella Soleti

IPC分类号： A61K38/17 ,  A61P9/06 ,  A61P9/10 ,  C07K14/47 ,  A61K9/16 ,  A61K9/00

CPC分类号： A61K38/1709 ,  A61K9/0019 ,  A61K9/16 ,  A61P9/06 ,  A61P9/10 ,  C07K14/47 ,  C07K14/4705 ,  C07K2319/30

摘要： The present invention relates to methods and pharmaceutical compositions for cardioprotection of subjects who experienced a myocardial infarction. In particular, the present invention relates to a ligand of the sonic hedgehog signaling pathway for use in the cardioprotection of a subject who experienced a myocardial infarction.