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公开(公告)号:US20070274992A1
公开(公告)日:2007-11-29
申请号:US10554816
申请日:2004-04-30
CPC分类号: C07K14/47 , A61K38/00 , Y02A90/26 , Y10T436/143333
摘要: This invention relates to a new family of secreted proteins, termed the SECFAM3 family, its family members including the novel human proteins INSP123, INSP124, and INSP125, herein identified as secreted proteins containing a von Willebrand Factor type C (vWFC) domain, and to the use to these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention, and treatment of disease.
摘要翻译: 本发明涉及称为SECFAM3家族的新型分泌蛋白家族,其家族成员包括新型人蛋白质INSP123,INSP124和INSP125,其鉴定为含有von Willebrand因子C型(vWFC)结构域的分泌蛋白质,以及 用于这些蛋白质和核酸序列的编码基因的诊断,预防和治疗疾病。
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公开(公告)号:US20070021590A1
公开(公告)日:2007-01-25
申请号:US10547529
申请日:2004-03-24
CPC分类号: C07K14/475 , A61K38/1808 , C07K14/47 , G16B30/00
摘要: This invention relates to a new family of secreted proteins, termed the SECFAMI family, its family members including the novel proteins INSP113, INSP114, INSP115, INSP116 and INSP117, herein identified as secreted proteins containing epidermal growth factor (EGF) fold-containing domains, ranging from 125-153 amino acids in length and containing eight conserved cysteine residues and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
摘要翻译: 本发明涉及一种称为SECFAMI家族的新型分泌蛋白家族,其家族成员包括新型蛋白INSP113,INSP114,INSP115,INSP116和INSP117,这些鉴定为含有表皮生长因子(EGF)折叠结构域的分泌蛋白, 长度为125-153个氨基酸,含有8个保守的半胱氨酸残基,以及来自编码基因的这些蛋白质和核酸序列在诊断,预防和治疗疾病中的应用。
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