公开(公告)号：US20110165586A1

公开(公告)日：2011-07-07

申请号：US12900248

申请日：2010-10-07

Applicant: Bongsoo Kim ,  Taejoon Kang ,  Ilsun Yoon ,  Sang Yup Lee ,  Seung Min Yoo

Inventor： Bongsoo Kim ,  Taejoon Kang ,  Ilsun Yoon ,  Sang Yup Lee ,  Seung Min Yoo

IPC: G01N33/53 ,  G01N21/00 ,  G01N33/48

CPC classification number: G01N21/658 ,  Y10T436/143333

Abstract: Provided is a detection method of a biochemical material using surface-enhanced Raman scattering in order to detect the existence of a biochemical material in a target subject or its content therein, more particularly a detection method of a biochemical material facilitating multiplex detection with high-sensitivity, high-reproducibility, high-reliability, and high-precision owing to multiple hot spots formed on the nanowire surface of a single crystal body by the bond of multiple nanoparticles which are physically separated from each other.

Abstract translation: 提供了使用表面增强拉曼散射来生物化学材料的检测方法，以检测目标受试者中的生物化学物质的存在或其含量，更具体地说，一种促进多重检测的生化材料的检测方法，具有高灵敏度 由于通过物理上彼此分离的多个纳米颗粒的结合而在单晶体的纳米线表面上形成的多个热点，具有高再现性，高可靠性和高精度。

公开(公告)号：US20100129261A1

公开(公告)日：2010-05-27

申请号：US12654665

申请日：2009-12-29

Applicant: Bongsoo Kim ,  Ilsun Yoon ,  Taejoon Kang

Inventor： Bongsoo Kim ,  Ilsun Yoon ,  Taejoon Kang

IPC: G01N21/47 ,  G01J3/44 ,  G01N21/84 ,  G01N21/75

CPC classification number: G01N33/54373 ,  G01N21/658

Abstract: The spectral sensor for surface-enhanced Raman scattering (SERS) of the present invention is prepared with a single-crystal noble metal nanowire which has a high quality, a high purity and an excellent shape. Thus, the sensor can be used for in-situ detection. Further, since a sensor site for reacting with irradiated laser beam can have a controlled structure, shape and a controllable hot spot, reliability and reproducibility are excellent and sensitivity of the sensor can be improved. In addition, with the optimization of a mechanical structure of a single noble metal single-crystal nanowire and a polarization direction of laser beam, sensitivity, selectivity and signal intensity become high. Furthermore, the spectral sensor for surface-enhanced Raman scattering of the present invention can be advantageously used not only as a sensor for detecting chemicals but also as a biosensor and a sensor for diagnosis of disease.

Abstract translation: 本发明的用于表面增强拉曼散射（SERS）的光谱传感器由具有高质量，高纯度和优异形状的单晶贵金属纳米线制备。 因此，传感器可用于原位检测。 此外，由于用于与照射的激光束反应的传感器位置可以具有受控的结构，形状和可控的热点，可靠性和再现性优异，并且可以提高传感器的灵敏度。 另外，通过优化单个贵金属单晶纳米线的机械结构和激光束的偏振方向，灵敏度，选择性和信号强度变高。 此外，本发明的用于表面增强拉曼散射的光谱传感器不仅可以有利地用作用于检测化学品的传感器，而且可以用作生物传感器和用于诊断疾病的传感器。