公开(公告)号：US20070184090A1

公开(公告)日：2007-08-09

申请号：US11711086

申请日：2007-03-20

申请人： Isabel Van Waterschoot ,  Hugo Streekstra

发明人： Isabel Van Waterschoot ,  Hugo Streekstra

IPC分类号： A61K31/202 ,  A61K47/00

CPC分类号： A61K31/202 ,  A23K20/158 ,  A23L33/12 ,  A61K31/20 ,  A61K2300/00

摘要： Edible formulations, such as polyunsaturated fatty acids (PUFAs) such as pharmaceutical compositions or nutritional supplements, are disclosed comprising arachidonic acid (ARA). They are adapted to deliver from 150 mg to 1 g per day of ARA and may contain other PUFAs, for example docosahexaenoic acid (DHA). The DHA dosage is from 400 to 600 mg per day, and the ratio of ARA:DHA may be from 1:5 to 5:1. Pharmaceutical compositions comprising ARA and DHA at a ratio of ARA:DHA of 1:1 to 1:2 are also disclosed, as are foodstuffs comprising 0.1 to 5% ARA. Such formulations can be used to increase ARA levels in vivo, for example in pregnant women or for people who have diseases or conditions associated with low ARA levels.

摘要翻译： 公开了食用制剂，例如多不饱和脂肪酸（PUFAs），例如药物组合物或营养补充剂，其包括花生四烯酸（ARA）。 它们适于每天从150mg递送至1g，并可含有其它PUFA，例如二十二碳六烯酸（DHA）。 DHA剂量为每天400至600mg，ARA：DHA的比例可以为1:5至5:1。 还公开了包含ARA：DHA比为1:1至1:2的ARA和DHA的药物组合物，以及包含0.1至5％ARA的食品。 这样的制剂可用于增加体内的ARA水平，例如在孕妇或具有低ARA水平相关疾病或病症的人群中。