Measuring respiratory mechanics parameters using perturbations

    公开(公告)号:US10188317B2

    公开(公告)日:2019-01-29

    申请号:US14815466

    申请日:2015-07-31

    摘要: According to one embodiment of the present invention, a method of determining respiratory parameters comprises determining a ratio of pressure changes to flow changes induced in the breathing of a patient by an airflow perturbation device at each of a plurality of perturbation frequencies to form a dataset. Resistance, compliance, and inertance parameters of a model of a respiratory system are determined by comparing a predicted frequency dependence of the model to the dataset. Embodiments of the present invention further include a system and computer program product for determining respiratory parameters in substantially the same manners described above.

    Detecting temperature sensitivity of a patient's airway

    公开(公告)号:US09895082B2

    公开(公告)日:2018-02-20

    申请号:US14815428

    申请日:2015-07-31

    摘要: According to one embodiment of the present invention, an airflow perturbation device for detecting airway sensitivity to temperature comprises a pneumotachometer including a flow sensor to measure airflow through the apparatus; a perturbation mechanism to periodically alter air flow resistance in the apparatus; an air cooler; a pressure sensor to measure a difference in air pressure across the pneumotachometer and perturbation mechanism; and a computing system comprising at least one processor configured to receive data from the flow sensor and pressure sensor; and determine an airflow resistance based on the received data. Embodiments of the present invention further include a method for detecting airway sensitivity to temperature in substantially the same manners described above.

    Measuring respiratory mechanics parameters of ventilated patients

    公开(公告)号:US10335565B2

    公开(公告)日:2019-07-02

    申请号:US14815442

    申请日:2015-07-31

    摘要: An airflow perturbation device for measuring respiratory resistance of a patient breathing with the use of a ventilator comprises a sealed housing having a first port and a second port each configured to couple to a ventilator hose, a perturbation mechanism to periodically alter air flow resistance between the first port and the second port, a pneumotachometer comprising a flow sensor to measure airflow between the first port and the second port, a pressure sensor to measure a difference in air pressure between the first port and the second port, and a computing system comprising at least one processor configured to receive data from the flow sensor and pressure sensor. The computing system determines an airflow resistance based on the received data. Embodiments of the present invention further include a method and computer program product for measuring respiratory resistance of a ventilated patient in substantially the same manners described above.

    MEASURING RESPIRATORY MECHANICS PARAMETERS USING PERTURBATIONS
    4.
    发明申请
    MEASURING RESPIRATORY MECHANICS PARAMETERS USING PERTURBATIONS 审中-公开
    使用PERTURBATIONS测量呼吸机械参数

    公开(公告)号:US20160038057A1

    公开(公告)日:2016-02-11

    申请号:US14815466

    申请日:2015-07-31

    IPC分类号: A61B5/085 A61B5/00 A61B5/09

    摘要: According to one embodiment of the present invention, a method of determining respiratory parameters comprises determining a ratio of pressure changes to flow changes induced in the breathing of a patient by an airflow perturbation device at each of a plurality of perturbation frequencies to form a dataset. Resistance, compliance, and inertance parameters of a model of a respiratory system are determined by comparing a predicted frequency dependence of the model to the dataset. Embodiments of the present invention further include a system and computer program product for determining respiratory parameters in substantially the same manners described above.

    摘要翻译: 根据本发明的一个实施例,一种确定呼吸参数的方法包括确定在多个扰动频率中的每一个处的气流扰动装置在患者的呼吸中诱导的压力变化与流动变化的比率,以形成数据集。 通过将模型的预测频率依赖性与数据集进行比较来确定呼吸系统模型的电阻,顺应性和惯性参数。 本发明的实施例还包括用于基本上以上述方式确定呼吸参数的系统和计算机程序产品。

    MEASURING RESPIRATORY MECHANICS PARAMETERS OF VENTILATED PATIENTS
    5.
    发明申请
    MEASURING RESPIRATORY MECHANICS PARAMETERS OF VENTILATED PATIENTS 审中-公开
    测量通气患者呼吸机制参数

    公开(公告)号:US20160038697A1

    公开(公告)日:2016-02-11

    申请号:US14815442

    申请日:2015-07-31

    IPC分类号: A61M16/00 A61M16/08

    摘要: An airflow perturbation device for measuring respiratory resistance of a patient breathing with the use of a ventilator comprises a sealed housing having a first port and a second port each configured to couple to a ventilator hose, a perturbation mechanism to periodically alter air flow resistance between the first port and the second port, a pneumotachometer comprising a flow sensor to measure airflow between the first port and the second port, a pressure sensor to measure a difference in air pressure between the first port and the second port, and a computing system comprising at least one processor configured to receive data from the flow sensor and pressure sensor. The computing system determines an airflow resistance based on the received data. Embodiments of the present invention further include a method and computer program product for measuring respiratory resistance of a ventilated patient in substantially the same manners described above.

    摘要翻译: 用于通过使用呼吸机测量患者呼吸阻力的气流扰动装置包括密封壳体,其具有第一端口和第二端口,每个端口和第二端口配置成耦合到呼吸机软管,扰动机构,以周期性地改变呼吸机之间的气流阻力 第一端口和第二端口,包括用于测量第一端口和第二端口之间的气流的流量传感器的气动计数器,用于测量第一端口和第二端口之间的空气压力差的压力传感器,以及计算系统, 至少一个处理器被配置为从流量传感器和压力传感器接收数据。 计算系统基于接收到的数据确定气流阻力。 本发明的实施例还包括用于以基本相同的方式测量通气患者的呼吸阻力的方法和计算机程序产品。

    DETECTING TEMPERATURE SENSITIVITY OF A PATIENT'S AIRWAY
    6.
    发明申请
    DETECTING TEMPERATURE SENSITIVITY OF A PATIENT'S AIRWAY 审中-公开
    检测患者空气的温度敏感性

    公开(公告)号:US20160038056A1

    公开(公告)日:2016-02-11

    申请号:US14815428

    申请日:2015-07-31

    摘要: According to one embodiment of the present invention, an airflow perturbation device for detecting airway sensitivity to temperature comprises a pneumotachometer including a flow sensor to measure airflow through the apparatus; a perturbation mechanism to periodically alter air flow resistance in the apparatus; an air cooler; a pressure sensor to measure a difference in air pressure across the pneumotachometer and perturbation mechanism; and a computing system comprising at least one processor configured to receive data from the flow sensor and pressure sensor; and determine an airflow resistance based on the received data. Embodiments of the present invention further include a method for detecting airway sensitivity to temperature in substantially the same manners described above.

    摘要翻译: 根据本发明的一个实施例,用于检测对温度的气道敏感性的气流扰动装置包括:气动测速计,其包括用于测量通过所述装置的气流的流量传感器; 周期性地改变设备中气流阻力的扰动机制; 空气冷却器 压力传感器,用于测量气动测速计和扰动机构之间的气压差; 以及计算系统,包括被配置为从所述流量传感器和压力传感器接收数据的至少一个处理器; 并基于所接收的数据确定气流阻力。 本发明的实施方式还包括以与上述基本相同的方式检测气道对气温敏感性的方法。