利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

7 条记录 (耗时 0.017 秒)

    Method for delivering oxygen to a cell culture medium
    2.
    发明授权
    Method for delivering oxygen to a cell culture medium 失效
    将氧气输送到细胞培养基的方法

    公开(公告)号：US5364784A

    公开(公告)日：1994-11-15

    申请号：US972366

    申请日：1992-11-05

    申请人： Richard Fike ,  James M. Kubiak

    发明人： Richard Fike ,  James M. Kubiak

    IPC分类号： C12M1/04 ,  C12M1/12 ,  C12N5/00

    CPC分类号： C12M29/04 ,  C12M29/24 ,  Y10S435/818

    摘要： An apparatus and method for delivering oxygen to a cell culture medium is disclosed. In one embodiment, the apparatus includes a transfer chamber placed within the cell culture medium. The transfer chamber is adapted to allow the cell culture medium to come in substantial contact with a liquid chemical that is passing through transfer chamber. The apparatus further includes a vessel placed outside the cell culture medium that serves to contain and continually recharge the liquid chemical. The apparatus further includes a plurality of pumps and tubes for circulating the liquid chemical through the transfer chamber and back to the vessel. When the liquid chemical comes into contact with the cell culture medium, oxygen is transferred from the liquid chemical to the cell culture medium.

    摘要翻译： 公开了一种将氧递送至细胞培养基的装置和方法。 在一个实施方案中，该装置包括置于细胞培养基内的转移室。 转移室适于使细胞培养基与通过转移室的液体化学品基本接触。 该装置还包括放置在细胞培养基外部的容器，其用于容纳并持续对液体化学品进行再充电。 该装置还包括多个泵和管，用于使液体化学品循环通过传送室并返回容器。 当液体化学品与细胞培养基接触时，氧气从液体化学品转移到细胞培养基中。

    Automated liquid manufacturing system
    3.
    发明授权
    Automated liquid manufacturing system 有权

    公开(公告)号：US06432143B1

    公开(公告)日：2002-08-13

    申请号：US09790623

    申请日：2001-02-23

    申请人： James M. Kubiak ,  Todd A. Battistoni ,  David W. Jayme

    发明人： James M. Kubiak ,  Todd A. Battistoni ,  David W. Jayme

    IPC分类号： B01F500

    摘要： A method and apparatus for continuously preparing a medium formulation mixes a diluent with a plurality of chemically incompatible concentrate solutions in such a manner that none of the ingredients of the concentrate solutions chemically react in an adverse manner. The method utilizes a static mixing chamber to add the concentrate solutions to the diluent stream sufficiently in advance of one another so that adverse chemical reactions do not occur. The method also adjusts a pH level of the diluent prior to adding any of the concentrate solutions to the diluent.

    System for delivering oxygen to a cell culture medium
    7.
    发明授权
    System for delivering oxygen to a cell culture medium 失效
    将氧气输送到细胞培养基的系统

    公开(公告)号：US5268298A

    公开(公告)日：1993-12-07

    申请号：US691801

    申请日：1991-04-26

    申请人： Richard Fike ,  James M. Kubiak

    发明人： Richard Fike ,  James M. Kubiak

    IPC分类号： C12M1/04 ,  C12M1/12 ,  C12M3/00

    CPC分类号： C12M29/04 ,  C12M29/24 ,  Y10S435/818

    摘要： An apparatus and method for delivering oxygen to a cell culture medium is disclosed. In one embodiment, the apparatus includes a transfer chamber placed within the cell culture medium. The transfer chamber is adapted to allow the cell culture medium to come in substantial contact with a liquid chemical that is passing through transfer chamber. The apparatus further includes a vessel placed outside the cell culture medium that serves to contain and continually recharge the liquid chemical. The apparatus further includes a plurality of pumps and tubes for circulating the liquid chemical through the transfer chamber and back to the vessel. When the liquid chemical comes into contact with the cell culture medium, oxygen is transferred from the liquid chemical to the cell culture medium.

    摘要翻译： 公开了一种将氧递送至细胞培养基的装置和方法。 在一个实施方案中，该装置包括置于细胞培养基内的转移室。 转移室适于使细胞培养基与通过转移室的液体化学品基本接触。 该装置还包括放置在细胞培养基外部的容器，其用于容纳并持续对液体化学品进行再充电。 该装置还包括多个泵和管，用于使液体化学品循环通过传送室并返回容器。 当液体化学品与细胞培养基接触时，氧气从液体化学品转移到细胞培养基中。