-
1.发明授权Compositions and methods for identifying and differentiating viral components of multivalent shipping fever vaccines 有权用于鉴定和鉴别多种运输发热疫苗的病毒组分的组合物和方法公开(公告)号：US09238843B2
公开(公告)日：2016-01-19
申请号：US13995707
申请日：2011-12-21
IPC分类号： C12Q1/70
摘要： Disclosed are methods and compositions for identifying viral-specific polynucleotide sequences in a biological sample, and particularly in samples of veterinary origin. Also disclosed are oligonucleotide primer pairs, as well as labeled oligonucleotide detection probes useful in detecting the presence of one or more particular species, strains, types, or subtypes of one or more mammalian pathogens of viral origin, as well as systems, diagnostic kits and articles of manufacture comprising virus-specific primers and labeled detection probes, including those useful in identifying viral components of a multivalent vaccine, and quantitating the potency of particular attenuated, live viruses that comprise a livestock vaccine. In certain embodiments, real-time, quantitative PCR methods have been utilized to identify and distinguish between the three known genetic subtypes of bovine viral diarrhea viruses (BVDV-1a, BVDV-1b, and BVDV-2) in a multivalent bovid shipping fever vaccine.
摘要翻译： 公开了用于鉴定生物样品中特别是兽类来源的样品中的病毒特异性多核苷酸序列的方法和组合物。 还公开了寡核苷酸引物对，以及可用于检测病毒来源的一种或多种哺乳动物病原体的一种或多种特定物种，菌株，类型或亚型的存在的标记的寡核苷酸检测探针，以及系统，诊断试剂盒和 包括病毒特异性引物和标记的检测探针的制品，包括用于鉴定多价疫苗的病毒组分的那些，以及定量包含家畜疫苗的特定减毒活病毒的效力。 在某些实施方案中，已经使用实时定量PCR方法来鉴定和区分多价bovid运输发热疫苗中的三种已知的牛病毒性腹泻病毒（BVDV-1a，BVDV-1b和BVDV-2）的遗传亚型 。
-
2.发明申请公开(公告)号：US20130280294A1
公开(公告)日：2013-10-24
申请号：US13995688
申请日：2011-12-21
IPC分类号： A61K39/155
CPC分类号： A61K39/155 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/552 , A61K2039/70 , C12N2710/16734 , C12N2760/18534 , C12N2760/18634 , C12N2770/24321 , C12N2770/24334
摘要： Disclosed are immunogenic compositions, and methods for their use in the formulation and administration of therapeutic and prophylactic pharmaceutical agents. In particular, the invention provides immunogenic compositions and methods for preventing, treating, managing, and/or ameliorating a viral or microbial infection, or one or more symptoms thereof, including, for example, those infections giving rise to shipping fever, bovine respiratory disease complex, and/or bovine viral diarrhea, particularly in susceptible or infected animals.
摘要翻译： 公开了免疫原性组合物及其在配制和施用治疗和预防药剂中的用途。 特别地，本发明提供用于预防，治疗，管理和/或改善病毒或微生物感染或其一种或多种症状的免疫原性组合物和方法，包括例如引起发热，牛呼吸道疾病 复杂和/或牛病毒性腹泻，特别是易感染或感染动物。
-
3.发明申请COMPOSITIONS AND METHODS FOR IDENTIFYING AND DIFFERENTIATING VIRAL COMPONENTS OF MULTIVALENT SHIPPING FEVER VACCINES 有权用于识别和分化多种运输费用疫苗的病毒组分的组合物和方法公开(公告)号：US20130266934A1
公开(公告)日：2013-10-10
申请号：US13995707
申请日：2011-12-21
IPC分类号： C12Q1/70
摘要： Disclosed are methods and compositions for identifying viral-specific polynucleotide sequences in a biological sample, and particularly in samples of veterinary origin. Also disclosed are oligonucleotide primer pairs, as well as labeled oligonucleotide detection probes useful in detecting the presence of one or more particular species, strains, types, or subtypes of one or more mammalian pathogens of viral origin, as well as systems, diagnostic kits and articles of manufacture comprising virus-specific primers and labeled detection probes, including those useful in identifying viral components of a multivalent vaccine, and quantitating the potency of particular attenuated, live viruses that comprise a livestock vaccine. In certain embodiments, real-time, quantitative PCR methods have been utilized to identify and distinguish between the three known genetic subtypes of bovine viral diarrhea viruses (BVDV-1a, BVDV-1b, and BVDV-2) in a multivalent bovid shipping fever vaccine.
摘要翻译： 公开了用于鉴定生物样品中特别是兽类来源的样品中的病毒特异性多核苷酸序列的方法和组合物。 还公开了寡核苷酸引物对，以及可用于检测病毒来源的一种或多种哺乳动物病原体的一种或多种特定物种，菌株，类型或亚型的存在的标记的寡核苷酸检测探针，以及系统，诊断试剂盒和 包括病毒特异性引物和标记的检测探针的制品，包括用于鉴定多价疫苗的病毒组分的那些，以及定量包含家畜疫苗的特定减毒活病毒的效力。 在某些实施方案中，已经使用实时定量PCR方法来鉴定和鉴别在多价bovid运输发热疫苗中的三种已知的牛病毒性腹泻病毒（BVDV-1a，BVDV-1b和BVDV-2）的遗传亚型 。
-
-
搜索结果
3 条记录 (耗时 0.025 秒)
