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公开(公告)号:US20050192221A1
公开(公告)日:2005-09-01
申请号:US11003126
申请日:2004-12-03
申请人: Paul McCray , Jerry Weiss , Hong Jia , Brian Schutte , Jennifer Bartlett
发明人: Paul McCray , Jerry Weiss , Hong Jia , Brian Schutte , Jennifer Bartlett
IPC分类号: A61K31/4745 , A61K31/496 , A61K31/65 , A61K31/704 , A61K31/7048 , A61K38/17
CPC分类号: A61K38/1709
摘要: The present invention concerns compositions and methods related to the use of peptides and polypeptides corresponding to all or part of the SPLUNC1 and LPLUNC1 proteins. Particular aspects of the invnetion include the use of SPLUNC1 and LPLUNC1 peptides and polypeptides as antimicrobials, anti-inflammatory, and immune modulatory agents.
摘要翻译: 本发明涉及与使用与全部或部分SPLUNC1和LPLUNC1蛋白相对应的肽和多肽相关的组合物和方法。 侵入的特定方面包括使用SPLUNC1和LPLUNC1肽和多肽作为抗微生物剂,抗炎剂和免疫调节剂。
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2.
公开(公告)号:US07951781B2
公开(公告)日:2011-05-31
申请号:US11934581
申请日:2007-11-02
申请人: Paul B. McCray, Jr. , Lokesh Gakhar , Rama K. Mallampalli , Subramanian Ramaswamy , Jennifer Bartlett
发明人: Paul B. McCray, Jr. , Lokesh Gakhar , Rama K. Mallampalli , Subramanian Ramaswamy , Jennifer Bartlett
IPC分类号: A61K38/08 , A61K38/16 , A61K39/215 , C07K14/135
CPC分类号: A61K45/06 , A61K31/43 , A61K31/66 , A61K31/685 , A61K38/1709 , A61K38/395 , A61K2300/00
摘要: Embodiments include compositions and methods for lower the surface tension of a liquid-air interface by contacting such interface with all or part of a PLUNC polypeptide.
摘要翻译: 实施方案包括通过使这种界面与全部或部分PLUNC多肽接触来降低液 - 空界面的表面张力的组合物和方法。
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3.
公开(公告)号:US20090110756A1
公开(公告)日:2009-04-30
申请号:US11934581
申请日:2007-11-02
申请人: Paul B. McCray, JR. , Lokesh Gakhar , Rama K. Mallampalli , Subramanian Ramaswamy , Jennifer Bartlett
发明人: Paul B. McCray, JR. , Lokesh Gakhar , Rama K. Mallampalli , Subramanian Ramaswamy , Jennifer Bartlett
CPC分类号: A61K45/06 , A61K31/43 , A61K31/66 , A61K31/685 , A61K38/1709 , A61K38/395 , A61K2300/00
摘要: Embodiments include compositions and methods for lower the surface tension of a liquid-air interface by contacting such interface with all or part of a PLUNC polypeptide.
摘要翻译: 实施方案包括通过使这种界面与全部或部分PLUNC多肽接触来降低液 - 空界面的表面张力的组合物和方法。
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