公开(公告)号：US20050095726A1

公开(公告)日：2005-05-05

申请号：US10892423

申请日：2004-07-14

Applicant: Xiangming Fang ,  Lei Huang ,  Ping Lin ,  Jerald Feitelson ,  Wei-Wei Zhang

Inventor： Xiangming Fang ,  Lei Huang ,  Ping Lin ,  Jerald Feitelson ,  Wei-Wei Zhang

IPC: C07K1/22 ,  C07K16/02 ,  C07K16/16 ,  C07K16/18 ,  C07K16/42 ,  G01N33/543

CPC classification number: C07K16/42 ,  C07K1/22 ,  C07K16/18 ,  C07K16/4283 ,  C07K2317/23

Abstract: Affinity separation compositions and methods are disclosed for separating targets from complex mixtures. Affinity reagents are bound to a solid support oriented in a manner to facilitate the activity of the affinity reagents which are capable of binding specific targets by affinity recognition. Affinity reagents include IgY antibodies, proteins, peptides, nucleotides and polymers. Targets include proteins, protein-protein complexes, protein-nucleotide complexes, nucleotides, cells and subcellular organelles.

Abstract translation: 公开了亲和力分离组合物和方法用于从复杂混合物中分离靶物。 亲和试剂结合固体支持物，其方式是促进能够通过亲和力识别结合特异性靶标的亲和试剂的活性。 亲和试剂包括IgY抗体，蛋白质，肽，核苷酸和聚合物。 目标包括蛋白质，蛋白质 - 蛋白质复合物，蛋白质 - 核苷酸复合物，核苷酸，细胞和亚细胞器。