摘要:
The present invention relates to a high-yield method for preparing highly pure (3S,4S)-4-((R)-2-(benzyloxy)tridecyl)-3-hexyl-2-oxetanone using a metal salt of (2S,3S,5R)-2-hexyl-3,5-dihydroxyhexadecanoic acid as an intermediate.
摘要:
Optically pure voriconazole can be prepared in a high yield by a) subjecting 1-(2,4-difluorophenyl)-2(1H-1,2,4-triazol-1-yl)ethanone to Reformatsky-type coupling reaction with a substituted thiopyrimidine derivative to obtain a desired (2R,3S)/(2S,3R)-enantiomeric pair; b) removing the thiol derivative from the enantiomer to obtain racemic voriconazole; and c) isolating the racemic voriconazole by way of optical resolution using an optically active acid.
摘要:
Optically pure voriconazole can be prepared in a high yield by a) subjecting 1-(2,4-difluorophenyl)-2(1H-1,2,4-triazol-1-yl)ethanone to Reformatsky-type coupling reaction with a substituted thiopyrimidine derivative to obtain a desired (2R,3S)/(2S,3R)-enantiomeric pair; b) removing the thiol derivative from the enantiomer to obtain racemic voriconazole; and c) isolating the racemic voriconazole by way of optical resolution using an optically active acid.
摘要:
Provided is a method of preparing a (6R)-3-hexyl-4-hydroxy-6-undecyl-5,6-dihydropyran-2-one, and a (5R)-2-hexyl-5-hydroxy-3-iminohexadecanoate derivative used in said method as an intermediate.
摘要:
System and method for providing a Web content provision service using a subscriber terminal in an exchange system. The Web content provision service system comprises the subscriber terminal generating content request information containing user information in response to a content request, receiving content information according to the content request information, and displaying the received content information on a display, a Web server for collecting the content information from at least one predetermined Web site at intervals of a certain time, storing the collected content information, accessing the stored content information in response to a message requesting transmission of the content information and sending the accessed content information to the subscriber terminal, and the exchange system having identification information corresponding to the subscriber terminal and port information corresponding to the identification information, being connected to an Internet protocol (IP) network via a local area network (LAN) and being connected to a public switched telephone network (PSTN) via a trunk card, sending the content transmission request message to the Web server over the Internet protocol network in response to the content request information from the subscriber terminal, receiving the content information according to the content request information from the Web server, and sending the received content information to the subscriber terminal.
摘要:
A method and apparatus for call conferencing between multiline subscribers in a telephone exchange system, the multiline subscribers having at least one phone number jointly and at least one common key, each common key representing a corresponding joint phone number. A common key of a corresponding joint phone number is pressed to set up a conference call while a multiline subscriber is communicating with or making a conference call to a subscriber.
摘要:
Disclosed herein is an apparatus for forming an electrode on a surface of a ceramic laminate. The apparatus for forming an electrode includes: a blast surface plate having ruggedness to which an electrode material paste is applied; and a moving device moving a ceramic laminate so that the ceramic laminate contacts the blast surface plate.
摘要:
A method for operating wired and wireless phone services interconnectively, includes: receiving a subscriber registration application for wired and wireless services from an arbitrary extension subscriber; performing wired and wireless service registrations in each of the extension subscribers by endowing at least one of the wired terminals and public/private mobile communication terminals with a wired phone number in accordance with the subscriber registration application; making a call to the wired terminal corresponding to the corresponding wired phone number in the case that an arbitrary wired phone number is called, and making a call to the corresponding public/private mobile communication terminal through a mobile communication network in the case that there is the public/private mobile communication terminal to be called simultaneously interconnectively to the wired phone number; and performing a billing according to a usage of the wired and wireless services in each of the extension subscribers. Therefore, a general wired subscriber is provided with the wired phone service and a service of portability through the wireless terminal, and a subscriber's accounting burden can be reduced.
摘要:
Provided is a method of preparing a (6R)-3-hexyl-4-hydroxy-6-undecyl-5,6-dihydropyran-2-one, and a (5R)-2-hexyl-5-hydroxy-3-iminohexadecanoate derivative used in said method as an intermediate.
摘要:
The present invention relates to a bicyclic compound for modulating G protein-coupled receptors. The inventive compound provides preventing or treating a disease associated with the modulation of G protein-coupled receptors, particularly GPR119 G protein-coupled receptors.