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1.发明授权公开(公告)号：US07781417B2
公开(公告)日：2010-08-24
申请号：US10580856
申请日：2004-11-24
申请人： Jacques Defaye , Carmen Ortiz-Mellet , José Manuel Garcia-Fernandez , Juan M. Benito , Marta Gomez-Garcia , Jian-Xin Yu
发明人： Jacques Defaye , Carmen Ortiz-Mellet , José Manuel Garcia-Fernandez , Juan M. Benito , Marta Gomez-Garcia , Jian-Xin Yu
IPC分类号： A61K31/724 , C08B37/16
CPC分类号： A61K47/40 , A61K47/6951 , B82Y5/00 , C08B37/0012 , C08B37/0015
摘要： The invention relates to a compound according to the following general formula (I), in which: m represents an integer equal to 5, 6 or 7; n and n1 represent an integer from 1 to 5; the A groups represent, in particular, a hydrogenated atom; X represents O or S; Y represents, in particular, a group NR1, R1, representing, in particular, a hydrogenated atom; W represents CH or N; and Z represents, in particular, a hydrogenated atom.
摘要翻译： 本发明涉及根据以下通式（I）的化合物，其中：m表示等于5,6或7的整数; n和n1表示1〜5的整数， A基团特别表示氢化原子; X表示O或S; Y特别表示特别是氢化原子的基团NR 1，R 1， W表示CH或N; Z特别表示氢化原子。
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2.发明申请公开(公告)号：US20090264540A1
公开(公告)日：2009-10-22
申请号：US12468356
申请日：2009-05-19
申请人： Jacques DEFAYE , Carmen Ortiz-Mellet , Jose Manuel Garcia-Fernandez , Maria Gomez-Garcia , Kazimierz Chmurski , Jian-Xin Yu
发明人： Jacques DEFAYE , Carmen Ortiz-Mellet , Jose Manuel Garcia-Fernandez , Maria Gomez-Garcia , Kazimierz Chmurski , Jian-Xin Yu
CPC分类号： B82Y5/00 , A61K47/6951 , C08B37/0012 , C08B37/0015
摘要： The invention relates to a compound corresponding to general formula (I) wherein n is a whole number from 1-6, m is a whole number equal to 5, 6 or 7, R1 is an OH group, all R1 s are identical, Z is an NHX group, X is a hydrogen atom, and R is a hydrogen atom or a bioidentification element, with the proviso that the compound wherein n=1, m=6, Z=NH2 and R1=OH is excluded.
摘要翻译： 本发明涉及对应于通式（I）的化合物，其中n为1-6的整数，m为等于5,6或7的整数，R 1为OH基，全部R 1相同，Z 是NHX基团，X是氢原子，R是氢原子或生物鉴定元素，条件是排除n = 1，m = 6，Z = NH 2和R 1 = OH的化合物。
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3.发明申请Novel cyclodextrin dimers and derivatives thereof, methods for preparing them and their use, in particular, for the solubilizing pharmacologically active substances 失效新型环糊精二聚体及其衍生物，其制备方法及其用途，特别是用于增溶药理活性物质公开(公告)号：US20070082867A1
公开(公告)日：2007-04-12
申请号：US10580856
申请日：2004-11-24
申请人： Jacques Defaye , Carmen Ortiz-Mellet , Jose Manuel Garcia-Fernandez , Juan Benito , Marta Gomez-Garcia , Jian-Xin Yu
发明人： Jacques Defaye , Carmen Ortiz-Mellet , Jose Manuel Garcia-Fernandez , Juan Benito , Marta Gomez-Garcia , Jian-Xin Yu
IPC分类号： C08B37/10 , C08B37/00 , A61K31/727
CPC分类号： A61K47/40 , A61K47/6951 , B82Y5/00 , C08B37/0012 , C08B37/0015
摘要： The invention relates to a compound according to the following general formula (I), in which: m represents an integer equal to 5, 6 or 7; n and n1 represent an integer from 1 to 5; the A groups represent, in particular, a hydrogenated atom; X represents O or S; Y represents, in particular, a group NR1, R1, representing, in particular, a hydrogenated atom; W represents CH or N; and Z represents, in particular, a hydrogenated atom.
摘要翻译： 本发明涉及根据以下通式（I）的化合物，其中：m表示等于5,6或7的整数; n和n 1表示1至5的整数; A基团特别表示氢化原子; X表示O或S; Y特别表示NR 1，R 1，R 1，特别表示氢化原子; W表示CH或N; Z特别表示氢化原子。
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4.发明授权公开(公告)号：US07632941B2
公开(公告)日：2009-12-15
申请号：US10551343
申请日：2004-03-22
申请人： Jacques Defaye , Carmen Ortiz-Mellet , José Manuel Garcia-Fernandez , Maria Gomez-Garcia , Kazimierz Chmurski , Jian-Xin Yu
发明人： Jacques Defaye , Carmen Ortiz-Mellet , José Manuel Garcia-Fernandez , Maria Gomez-Garcia , Kazimierz Chmurski , Jian-Xin Yu
CPC分类号： B82Y5/00 , A61K47/6951 , C08B37/0012 , C08B37/0015
摘要： The invention relates to a cyclodextrin derivative corresponding to general formula (I) wherein n is a whole number from 1-6, m is a whole number equal to 5, 6 or 7, R1 is an OH group, all R1s are identical, Z is a thiourea group, X is a hydrogen atom, and R is a hydrogen atom or a bioidentification element.
摘要翻译： 本发明涉及对应于通式（I）的环糊精衍生物，其中n为1-6的整数，m为等于5,6或7的整数，R 1为OH基，所有R 1相同，Z 是硫脲基团，X是氢原子，R是氢原子或生物鉴定元素。
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5.发明申请公开(公告)号：US20070167401A1
公开(公告)日：2007-07-19
申请号：US10551343
申请日：2004-03-22
申请人： Jacques Defaye , Carmen Ortiz-Mellet , Jose Garcia-Fernandez , Maria Gomez-Garcia , Kazimierz Chmurski , Jian-Xin Yu
发明人： Jacques Defaye , Carmen Ortiz-Mellet , Jose Garcia-Fernandez , Maria Gomez-Garcia , Kazimierz Chmurski , Jian-Xin Yu
IPC分类号： A61K31/727 , A61K31/724 , C08B37/10 , C08B30/18
CPC分类号： B82Y5/00 , A61K47/6951 , C08B37/0012 , C08B37/0015
摘要： The invention relates to a compound corresponding to general formula (I) wherein n is a whole number from 1-6, m is a whole number equal to 5, 6 or 7, R1 is an OH group, all R1s are identical, Z is an NHX group, X is a hydrogen atom, and R is a hydrogen atom or a bioidentification element, with the proviso that the compound wherein n=1, m=6, Z=NH2 and R1=OH is excluded.
摘要翻译： 本发明涉及对应于通式（I）的化合物，其中n为1-6的整数，m为等于5,6或7的整数，R 1为OH基 ，所有R 1相同，Z为NHX基团，X为氢原子，R为氢原子或生物鉴定元件，条件是其中n = 1，m = 6，Z = NH 2和R 1 = OH被排除。
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6.发明授权Derivatives of cyclodextrins, process for their preparation and their use in particular for solubilizing pharmacologically active substances 失效环糊精的衍生物，其制备方法及其用途，特别是用于增溶药理活性物质公开(公告)号：US08440814B2
公开(公告)日：2013-05-14
申请号：US12468356
申请日：2009-05-19
申请人： Jacques Defaye , Carmen Ortiz-Mellet , Jose Manuel Garcia-Fernandez , Maria Gomez-Garcia , Kazimierz Chmurski , Jian-Xin Yu
发明人： Jacques Defaye , Carmen Ortiz-Mellet , Jose Manuel Garcia-Fernandez , Maria Gomez-Garcia , Kazimierz Chmurski , Jian-Xin Yu
IPC分类号： C08B37/16 , A01N43/04 , A61K31/715
CPC分类号： B82Y5/00 , A61K47/6951 , C08B37/0012 , C08B37/0015
摘要： The invention relates to a compound corresponding to general formula (I) wherein n is a whole number from 1-6, m is a whole number equal to 5, 6 or 7, R1 is an OH group, all R1 s are identical, Z is an NHX group, X is a hydrogen atom, and R is a hydrogen atom or a bioidentification element, with the proviso that the compound wherein n=1, m=6, Z=NH2 and R1=OH is excluded.
摘要翻译： 本发明涉及对应于通式（I）的化合物，其中n为1-6的整数，m为等于5,6或7的整数，R 1为OH基，全部R 1相同，Z 是NHX基团，X是氢原子，R是氢原子或生物鉴定元素，条件是排除n = 1，m = 6，Z = NH 2和R 1 = OH的化合物。
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