摘要:
A cathode electrode for lithium-ion secondary battery includes a current collector; and a cathode material layer comprising a bottom layer coated on the current collector and a top layer coated on the bottom layer. The lithium-ion transfer resistance of the active material particles in the bottom layer is smaller than that of the active material particles in the top layer, optimize the concentration polarization occurred in the cathode electrode during discharge, and enabling the lithium-ion secondary battery using the cathode electrode to be improved both in energy density and safety, and be further enhanced in specific capacity.
摘要:
A novel scalable synthesis for the preparation of 7-(3-pyridinyI)-1,7-diazaspiro[4.4)nonane has been developed, and 7-(3-pyridinyl)-1,7-diazaspiro[4.4]nonane salts have been formed with succinic acid and oxalic acid. Additionally, 7-(3-pyridinyl)-1,7-diaza-spiro[4.4]nonane has been separated into its stereoisomers via resolution with L and D di-p-toluoyltartaric acids, giving (R)- and (S)-7-(3-pyridinyl)-1,7-diazaspiro[4.4]nonane of high enantiomeric purity. Numerous solid salts of the resulting (R)- and (S)-7-(3-pyridinyl)-1,7-diazaspiro[4.4}nonane have been prepared. Methods for the preparation of the racemic and enantiomeric salts, pharmaceutical compositions comprising such salts, and uses thereof are disclosed. The salts can be administered to patients susceptible to or suffering from conditions and disorders, such as central nervous system disorders, to treat and/or prevent such disorders.