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公开(公告)号:US20110110958A1
公开(公告)日:2011-05-12
申请号:US12677705
申请日:2008-09-11
申请人: Jingxin Qiu , Mingli Yang , David A. Ostrov , W. Stratford May
发明人: Jingxin Qiu , Mingli Yang , David A. Ostrov , W. Stratford May
IPC分类号: A61K39/395 , A61K31/17 , A61K31/4188 , A61K31/713 , A61K31/7088 , C12N5/09 , C12Q1/02 , C12Q1/18 , G01N33/68 , A61K48/00 , A61P35/00 , A61P35/02 , G06G7/58
CPC分类号: A61K31/17
摘要: The invention provides compositions and methods for the treatment of neoplasias that are cytotoxic to neoplastic cells or that modulate JAZ expression, subcellular localization, or biological activity.
摘要翻译: 本发明提供了用于治疗对肿瘤细胞具有细胞毒性或调节JAZ表达,亚细胞定位或生物活性的肿瘤的组合物和方法。