公开(公告)号：US5011690A

公开(公告)日：1991-04-30

申请号：US202563

申请日：1988-06-06

申请人： Michael J. Garvey ,  Ian C. Griffiths ,  John H. S. Rennie

发明人： Michael J. Garvey ,  Ian C. Griffiths ,  John H. S. Rennie

IPC分类号： C01B33/18 ,  A01N25/12 ,  A61K8/25 ,  A61K9/14 ,  A61K9/16 ,  A61L9/04 ,  A61Q13/00 ,  A61Q19/00 ,  B01J13/04 ,  C01B33/12 ,  C01B33/187 ,  C09B63/00 ,  C09C1/30 ,  C11D3/12

CPC分类号： C11D3/124 ,  A01N25/12 ,  A61K8/25 ,  A61K9/143 ,  A61K9/1611 ,  A61K9/1694 ,  A61L9/046 ,  A61Q19/00 ,  B01J13/046 ,  C09B63/00 ,  C09C1/30 ,  A61K2800/412 ,  A61Q13/00 ,  C01P2004/32 ,  C01P2004/61 ,  C01P2006/14 ,  C01P2006/16 ,  C01P2006/17 ,  C01P2006/80 ,  Y10T428/2989

摘要： Porous spheroidal silica having a particle size in the range 1 to 400 microns, axial ratios of 1:1 to 1:12 has up to 50% by weight of the SiO.sub.2 of included material, such as for example perfumes, flavoring materials, pigments, germicides, bactericides, fungicides, bleaching agents, skin benefit agents, therapeutic agents, dispersed in the silica as particles or droplets in the size range 0.01 to 10 .mu.m. The spheroids can be made by mixing together an aqueous, stabilized silica sol containing dispersed therein up to 50% by weight of the silica of an included material and an aqueous solution of a non-adsorbing polymer to form a phase separated system comprising silica droplets containing included material in a polymer-rich continuous phase and condensing the silica sol to aggregate the droplets to form silica spheroids containing the dispersed included material. The included material can be released in use by e.g. wetting, attrition, dissolution, pH change, heating.

公开(公告)号：US5112612A

公开(公告)日：1992-05-12

申请号：US527888

申请日：1990-05-23

申请人： Michael J. Garvey ,  Ian C. Griffiths ,  John H. S. Rennie

发明人： Michael J. Garvey ,  Ian C. Griffiths ,  John H. S. Rennie

IPC分类号： A01N25/12 ,  A61K8/25 ,  A61K9/14 ,  A61K9/16 ,  A61L9/04 ,  A61Q13/00 ,  A61Q19/00 ,  B01J13/04 ,  C09B63/00 ,  C09C1/30 ,  C11D3/12

CPC分类号： C11D3/124 ,  A01N25/12 ,  A61K8/25 ,  A61K9/143 ,  A61K9/1611 ,  A61K9/1694 ,  A61L9/046 ,  A61Q19/00 ,  B01J13/046 ,  C09B63/00 ,  C09C1/30 ,  A61K2800/412 ,  A61Q13/00 ,  C01P2004/32 ,  C01P2004/61 ,  C01P2006/14 ,  C01P2006/16 ,  C01P2006/17 ,  C01P2006/80

摘要： Porous spheroidal silica having a particle size in the range 1 to 400 microns, axial ratios of 1:1 to 1:12 has up to 50% by weight of the SiO.sub.2 of included material, such as for example perfumes, flavoring materials, pigments, germicides, bactericides, fungicides, bleaching agents, skin benefit agents, therapeutic agents, dispersed in the silica as particles or droplets in the size range 0.01 to 10 .mu.m. The spheroids can be made by mixing together an aqueous, stabilized silica sol containing dispersed therein up to 50% by weight of the silica of an included material and an aqueous solution of a non-adsorbing polymer to form a phase separated system comprising silica droplets containing included material in a polymer-rich continuous phase and condensing the silica sol to aggregate the droplets to form silica spheroids containing the dispersed included material. The included material can be released in use by e.g. wetting, attrition, dissolution, pH change, heating.

摘要翻译： 粒径在1至400微米范围内的轴向比为1:1至1:12的多孔球状二氧化硅具有至多50重量％的所包括材料的SiO 2，例如香料，调味料，颜料， 杀菌剂，杀菌剂，杀真菌剂，漂白剂，皮肤有益剂，治疗剂，分散在二氧化硅中的颗粒或液滴，尺寸范围为0.01至10μm。 可以通过将包含分散在其中的含水稳定的二氧化硅溶胶混合到包含材料的二氧化硅的50重量％和非吸附聚合物的水溶液中来形成球状体，以形成包含二氧化硅微滴的相分离系统 将材料包含在富含聚合物的连续相中，并冷凝硅溶胶以聚集液滴以形成含有分散的包含材料的二氧化硅球体。 所包括的材料可以通过例如使用来释放。 润湿，磨损，溶解，pH变化，加热。