-
公开(公告)号:US20090191254A1
公开(公告)日:2009-07-30
申请号:US11720908
申请日:2005-12-06
申请人: John J. Curtin , Rodney M. Donlan
发明人: John J. Curtin , Rodney M. Donlan
CPC分类号: A61L31/16 , A61L29/16 , A61L2300/30 , A61L2300/404
摘要: Disclosed herein are indwelling medical devices suitable for introduction into the body of a subject, wherein the indwelling medical devices comprise one or more surfaces on which a bacterial biofilm can form, and an effective amount of a bacteriophage composition carried by one or more of the surfaces, wherein the bacteriophage composition inhibits formation of the bacterial biofilm on the indwelling medical device. Also disclosed herein are methods of inhibiting the formation of bacterial biofilms on indwelling medical devices.
摘要翻译: 本文公开了适合于引入受试者体内的留置医疗装置,其中所述留置医疗装置包括其上可以形成细菌生物膜的一个或多个表面,以及由一个或多个表面承载的有效量的噬菌体组合物 其中所述噬菌体组合物抑制所述留置医疗装置上的细菌生物膜的形成。 本文还公开了抑制在留置医疗装置上形成细菌生物膜的方法。