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公开(公告)号:US20130066402A1
公开(公告)日:2013-03-14
申请号:US13588957
申请日:2012-08-17
申请人: John Yu-luen Lin , Roger Y. Tsien
发明人: John Yu-luen Lin , Roger Y. Tsien
IPC分类号: C07K19/00 , A61N5/06 , C12N15/864 , C12N15/62 , C12N15/85
CPC分类号: C07K19/00 , A61K48/005 , A61N5/062 , C07K14/705 , C07K2319/00 , C12N15/62 , C12N15/85 , C12N15/864 , C12N2740/15043 , C12N2740/15071 , C12N2750/14143 , C12N2750/14171
摘要: The invention provides engineered red-shifted channelrhodopsin variants. In some embodiments, the channelrhodopsin variants are characterized by improved membrane trafficking, expression, and/or unique spectral and kinetic properties.
摘要翻译: 本发明提供工程化的红移通道视紫红质变体。 在一些实施方案中,通道视紫红质变体的特征在于改进的膜运输,表达和/或独特的光谱和动力学性质。
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公开(公告)号:US08759492B2
公开(公告)日:2014-06-24
申请号:US13588957
申请日:2012-08-17
申请人: John Yu-luen Lin , Roger Y. Tsien
发明人: John Yu-luen Lin , Roger Y. Tsien
CPC分类号: C07K19/00 , A61K48/005 , A61N5/062 , C07K14/705 , C07K2319/00 , C12N15/62 , C12N15/85 , C12N15/864 , C12N2740/15043 , C12N2740/15071 , C12N2750/14143 , C12N2750/14171
摘要: The invention provides engineered red-shifted channelrhodopsin variants. In some embodiments, the channelrhodopsin variants are characterized by improved membrane trafficking, expression, and/or unique spectral and kinetic properties.
摘要翻译: 本发明提供工程化的红移通道视紫红质变体。 在一些实施方案中,通道视紫红质变体的特征在于改进的膜运输,表达和/或独特的光谱和动力学性质。
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