公开(公告)号：US08999156B2

公开(公告)日：2015-04-07

申请号：US10591377

申请日：2005-03-04

申请人： Pamela C. Iraneta ,  Jon Belanger ,  Raymond P. Fisk

发明人： Pamela C. Iraneta ,  Jon Belanger ,  Raymond P. Fisk

IPC分类号： G01N30/60

CPC分类号： G01N30/603

摘要： A frit (44) includes a porous support structure having a plurality of void spaces, where a plurality of secondary particles (46) are filled in the void spaces, the secondary particles (46) being dimensioned with respect to the void spaces such that the frit (44) retains packing materials with diameters of less than about 2.5 microns. Preferably one or more frits (44) are received in a high pressure liquid chromatography (HPLC) chromatographic column, where the column includes fittings and filter assemblies for receiving frits (44) at its inlet and outlet. The frit (44) can be constructed from a porous support structure with void spaces or pores that are filled with secondary particles (46) smaller those used to manufacture the support. The particles (46) contained in the void spaces are large enough to be retained by the support, but small enough to create a finer network of interconnected channels within the support's void spaces that are capable of retaining sub-2.5 micrometer particles.

摘要翻译： 玻璃料（44）包括具有多个空隙空间的多孔支撑结构，其中多个二次颗粒（46）填充在空隙空间中，二次颗粒（46）相对于空隙空间的尺寸确定，使得 玻璃料（44）保留直径小于约2.5微米的包装材料。 优选地，一个或多个玻璃料（44）被接收在高压液相色谱（HPLC）色谱柱中，其中色谱柱包括用于在其入口和出口处接收玻璃料（44）的配件和过滤器组件。 玻璃料（44）可以由具有空隙空间或孔的多孔支撑结构构成，其填充有用于制造载体的二次颗粒（46）。 包含在空隙空间中的颗粒（46）足够大以被支撑体保持，但足够小以在支撑件的空隙空间内产生能够保持次2.5微米颗粒的互连通道的更细的网络。

公开(公告)号：US20070295663A1

公开(公告)日：2007-12-27

申请号：US10591377

申请日：2005-03-04

申请人： Pamela Iraneta ,  Jon Belanger ,  Raymond Fisk

发明人： Pamela Iraneta ,  Jon Belanger ,  Raymond Fisk

IPC分类号： B01D15/08

CPC分类号： G01N30/603

摘要： A frit (44) includes a porous support structure having a plurality of void spaces, where a plurality of secondary particles (46) are filled in the void spaces, the secondary particles (46) being dimensioned with respect to the void spaces such that the frit (44) retains packing materials with diameters of less than about 2.5 microns. Preferably one or more frits (44) are received in a high pressure liquid chromatography (HPLC) chromatographic column, where the column includes fittings and filter assemblies for receiving frits (44) at its inlet and outlet. The frit (44) can be constructed from a porous support structure with void spaces or pores that are filled with secondary particles (46) smaller those used to manufacture the support. The particles (46) contained in the void spaces are large enough to be retained by the support, but small enough to create a finer network of interconnected channels within the support's void spaces that are capable of retaining sub-2.5 micrometer particles.

摘要翻译： 玻璃料（44）包括具有多个空隙空间的多孔支撑结构，其中多个二次颗粒（46）填充在空隙空间中，二次颗粒（46）相对于空隙空间的尺寸确定，使得 玻璃料（44）保留直径小于约2.5微米的包装材料。 优选地，一个或多个玻璃料（44）被接收在高压液相色谱（HPLC）色谱柱中，其中色谱柱包括用于在其入口和出口处接收玻璃料（44）的配件和过滤器组件。 玻璃料（44）可以由具有空隙空间或孔的多孔支撑结构构成，其填充有用于制造载体的二次颗粒（46）。 包含在空隙空间中的颗粒（46）足够大以被支撑体保持，但足够小以在支撑件的空隙空间内产生能够保持次2.5微米颗粒的互连通道的更细的网络。