摘要:
Described herein are methods and compositions for expanding hematopoietic stem and progenitor cells (HSPC) ex vivo and in vivo, and methods and compositions for transplanting HSPCs and treatment of anemia in a human subject. HSPCs are expanded in the presence of an inhibitor of serine threonine kinase 38 (STK38), wherein said inhibitor is preferably an RNAi agent.
摘要:
Described herein are methods and compositions for expanding hematopoietic stem and progenitor cells (HSPC) ex vivo and in vivo, and methods and compositions for transplanting HSPCs and treatment of anemia in a human subject. HSPCs are expanded in the presence of an inhibitor of serine threonine kinase 38 (STK38), wherein said inhibitor is preferably an RNAi agent.
摘要:
A rotor disk for a rotor of a synchronous reluctance machine consists of a disk body material with high magnetic permeability. In order to improve the ability of the rotor disk to stand centrifugal and thermal loads, spokes extending in radial direction between a shaft opening and a disk periphery are provided with spoke openings. These openings extend over a wide distance both in circumferential direction and in radial direction to worsen the heat conducting properties of the spokes and to render the spokes less stiff.
摘要:
A masking arrangement for a gas turbine engine includes a plurality of annular elements arranged overlapping one another when these are viewed in an axial direction so as to mask at least a substantial portion of any interior hot and rotating gas turbine engine part at an aft end of the gas turbine engine from rear view when the masking arrangement is applied downstream the interior part in the gas turbine engine.
摘要:
A rotor disk for a rotor of a synchronous reluctance machine consists of a disk body material with high magnetic permeability. In order to improve the ability of the rotor disk to stand centrifugal and thermal loads, spokes extending in radial direction between a shaft opening and a disk periphery are provided with spoke openings. These openings extend over a wide distance both in circumferential direction and in radial direction to worsen the heat conducting properties of the spokes and to render the spokes less stiff.
摘要:
The invention relates to a gas turbine intermediate structure (14) for being arranged between a first and a second gas turbine structure (8 and 9) in an axial direction (18) of a gas turbine (1). The intermediate structure (14) comprises an gas duct (5c) arranged for guiding a gas flow from a gas duct (5a) in the first structure (8) to a gas duct (5b) in the second structure (9). An inlet (19) of the intermediate structure gas duct (5c) is substantially displaced in a radial direction in relation to an outlet (20) of the intermediate structure gas duct (5c). At least one guide vane (28,29) is arranged in the intermediate structure gas duct (5c) for guiding the gas flow.