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1.发明授权Signalin family of TGF&bgr; signal transduction proteins, and uses related thereto 失效Signalin家族的TGFbeta信号转导蛋白，以及与之相关的用途公开(公告)号：US06428977B1
公开(公告)日：2002-08-06
申请号：US08580031
申请日：1995-12-20
申请人： Jonathan M. Graff , Tod M. Woolf , Ping Jin , Douglas A. Melton
发明人： Jonathan M. Graff , Tod M. Woolf , Ping Jin , Douglas A. Melton
IPC分类号： C12N1512
CPC分类号： C12Q1/6886 , A61K48/00 , C07K14/4702 , C12Q2600/136
摘要： The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here signalin-related genes, which are involved in signal transduction induced by members of the TGF&bgr; superfamily. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
摘要翻译： 本发明涉及由脊椎动物家族（称为这里信号蛋白相关基因）编码的蛋白质的参与由TGFbeta超家族成员诱导的信号转导的蛋白质的发现。 本发明提供可用于例如在体外和体内产生和/或维持不同脊椎动物组织阵列的组合物和方法。
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2.发明授权“Signalin” family of TGFβ signal transduction proteins, and uses related thereto 有权“Signalin”家族的TGFbeta信号转导蛋白，以及与此有关的用途公开(公告)号：US07034114B2
公开(公告)日：2006-04-25
申请号：US10095492
申请日：2002-03-12
申请人： Jonathan M. Graff , Tod M. Woolf , Ping Jin , Douglas A. Melton
发明人： Jonathan M. Graff , Tod M. Woolf , Ping Jin , Douglas A. Melton
CPC分类号： C12Q1/6886 , A61K48/00 , C07K14/4702 , C12Q2600/136
摘要： The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here signalin-related genes, which are involved in signal transduction induced by members of the TGFβ superfamily. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
摘要翻译： 本发明涉及由脊椎动物家族（称为这里信号蛋白相关基因）编码的蛋白质的参与由TGFbeta超家族成员诱导的信号转导的蛋白质的发现。 本发明提供可用于例如在体外和体内产生和/或维持不同脊椎动物组织阵列的组合物和方法。
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