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公开(公告)号:US20130184439A1
公开(公告)日:2013-07-18
申请号:US13812654
申请日:2011-07-26
Applicant: Mariangela Spitali , Jonathan Symmons , Richard Whitcombe , Mark Robert Pearce-Higgins
IPC: C07K1/18
CPC classification number: C07K16/241 , C07K1/18 , C07K1/36 , C07K2317/14 , C07K2317/55
Abstract: The present invention relates to a process for the purification of an antibody fragment from a periplasmic cell extract comprising a first cation exchange chromatography step and a second anion exchange chromatography step.
Abstract translation: 本发明涉及从包含第一阳离子交换层析步骤和第二阴离子交换层析步骤的周质细胞提取物中纯化抗体片段的方法。
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公开(公告)号:US09309280B2
公开(公告)日:2016-04-12
申请号:US13812654
申请日:2011-07-26
Applicant: Mariangela Spitali , Jonathan Symmons , Richard Whitcombe , Mark Robert Pearce-Higgins
CPC classification number: C07K16/241 , C07K1/18 , C07K1/36 , C07K2317/14 , C07K2317/55
Abstract: The present invention relates to a process for the purification of an antibody fragment from a periplasmic cell extract comprising a first cation exchange chromatography step and a second anion exchange chromatography step.
Abstract translation: 本发明涉及从包含第一阳离子交换层析步骤和第二阴离子交换层析步骤的周质细胞提取物中纯化抗体片段的方法。
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