公开(公告)号：US08961965B2

公开(公告)日：2015-02-24

申请号：US13474459

申请日：2012-05-17

申请人： David L Gossage ,  Deepak B. Khatry ,  Gregory P. Geba ,  Nestor Molfino ,  Joseph M. Parker

发明人： David L Gossage ,  Deepak B. Khatry ,  Gregory P. Geba ,  Nestor Molfino ,  Joseph M. Parker

IPC分类号： A61K39/395 ,  G01N33/569 ,  G06F19/00

CPC分类号： G01N33/56972 ,  G01N2800/12 ,  G01N2800/52 ,  G01N2800/60 ,  G06F19/00 ,  G06F19/3456 ,  G16H50/20

摘要： The present disclosure provides methods of diagnosing a subject as having a pulmonary disease or disorder, e.g., an eosinophilic disease or disorder based on the determination of white blood cell ratios. The disclosure also provides white blood cell ratio-based methods of treating, prognosing, or monitoring a pulmonary disease or disorder, as well as methods of methods of predicting a dosage regimen, identifying a candidate therapeutic agent, identifying a patient as a candidate for a therapeutic agent, and methods of designing a personalized therapy.

摘要翻译： 本公开提供了基于白细胞比率的确定将受试者诊断为具有肺部疾病或病症，例如嗜酸细胞性疾病或病症的方法。 本公开还提供了基于白细胞比例的治疗，预后或监测肺部疾病或病症的方法，以及预测剂量方案的方法，鉴定候选治疗剂，鉴定患者作为候选治疗剂的候选者 治疗剂和设计个性化疗法的方法。

公开(公告)号：US20120328606A1

公开(公告)日：2012-12-27

申请号：US13474459

申请日：2012-05-17

申请人： David L. Gossage ,  Deepak B. Khatry ,  Gregory P. Geba ,  Nestor Molfino ,  Joseph M. Parker

发明人： David L. Gossage ,  Deepak B. Khatry ,  Gregory P. Geba ,  Nestor Molfino ,  Joseph M. Parker

IPC分类号： A61K39/395 ,  G06F19/00 ,  A61P9/00

CPC分类号： G01N33/56972 ,  G01N2800/12 ,  G01N2800/52 ,  G01N2800/60 ,  G06F19/00 ,  G06F19/3456 ,  G16H50/20

摘要： The present disclosure provides methods of diagnosing a subject as having a pulmonary disease or disorder, e.g., an eosinophilic disease or disorder based on the determination of white blood cell ratios. The disclosure also provides white blood cell ratio-based methods of treating, prognosing, or monitoring a pulmonary disease or disorder, as well as methods of methods of predicting a dosage regimen, identifying a candidate therapeutic agent, identifying a patient as a candidate for a therapeutic agent, and methods of designing a personalized therapy.

摘要翻译： 本公开提供了基于白细胞比率的确定将受试者诊断为具有肺部疾病或病症，例如嗜酸细胞性疾病或病症的方法。 本公开还提供了基于白细胞比例的治疗，预后或监测肺部疾病或病症的方法，以及预测剂量方案的方法，鉴定候选治疗剂，鉴定患者作为候选治疗剂的候选者 治疗剂和设计个性化疗法的方法。

公开(公告)号：US07172219B2

公开(公告)日：2007-02-06

申请号：US10957051

申请日：2004-10-01

申请人： Justin M. Spragg ,  Joseph M. Parker

发明人： Justin M. Spragg ,  Joseph M. Parker

IPC分类号： A63C11/22

CPC分类号： A63C11/221 ,  A63C5/03

摘要： Embodiments include a collapsible utility pole that snowboarders can carry easily in their pants pocket and can be quickly pulled out and extended to a completely rigid pole to push themselves over flat sections of downhill runs. The utility pole can also being useful when getting off the chair lift to move toward the slopes. Embodiments of the device have the capability of being converted into a small shovel or ice pick by detaching the snow basket and attaching a desired device.

摘要翻译： 实施例包括可滑行的实用杆，滑雪板可以容易地携带在裤子口袋中，并且可以被快速拉出并延伸到完全刚性的杆，以将它们自身推向下坡的平坦部分。 电梯杆也可用于下车时，升降梯向斜坡移动。 该装置的实施例具有通过分离雪筐并附接所需装置而被转换成小铲或冰镐的能力。