Antithrombotic agents
    1.
    发明授权
    Antithrombotic agents 失效
    抗血栓药

    公开(公告)号:US06417203B1

    公开(公告)日:2002-07-09

    申请号:US09662241

    申请日:2000-09-14

    IPC分类号: A61K314439

    摘要: Compounds of formula (I): are antithrombotic agents, having utility in a variety of therapeutic areas including the prevention and/or treatment of deep vein thrombosis (DVT) after surgery, major medical illness, paralysis, malignancy, prolonged immobilisation trauma, application of lower limb plaster casts, or fractures of the lower limbs or pelvis; recurrent DVT; DVT during pregnancy when there is a previous history thereof; reocclusion following thrombolytic therapy; chronic arterial obstruction; peripheral vascular disease; acute myocardial infarction; unstable angina; atrial fibrillation; thrombotic stroke; transient ischaemic attacks; disseminated intravascular coagulation; coagulation in extra-corporeal circuits; occlusion of arterio-venous shunts and blood vessel grafts (including coronary artery by-pass grafts); and restenosis and occlusion following angioplasty.

    摘要翻译: 式(I)化合物是抗血栓形成剂,可用于各种治疗领域,包括手术后预防和/或治疗深静脉血栓形成(DVT),主要医学疾病,麻痹,恶性肿瘤,长期固定创伤,应用 下肢石膏或下肢或骨盆骨折; 复发DVT; 怀孕期间DVT有先前的病史; 溶栓治疗后再闭塞; 慢性动脉阻塞; 周边血管疾病; 急性心肌梗塞; 不稳定型心绞痛; 房颤; 血栓性脑卒中 短暂性脑缺血发作; 弥散性血管内凝血; 额外体内循环中的凝血; 静脉分流和血管移植物(包括冠状动脉旁路移植物)的闭塞; 以及血管成形术后的再狭窄和闭塞。

    Antithrombotic agents
    3.
    发明授权
    Antithrombotic agents 失效
    抗血栓药

    公开(公告)号:US06180627B2

    公开(公告)日:2001-01-30

    申请号:US09372200

    申请日:1999-08-11

    IPC分类号: A61K315355

    摘要: Compounds of formula (I): Are antithrombotic agents, having utility in a variety of therapeutic areas including the prevention and/or treatment of deep vein thrombosis (DVT) after surgery, major medical illness, paralysis, malignancy, prolonged immobilisation trauma, application of lower limb plaster casts, or fractures of the lower limbs or pelvis; recurrent DVT; DVT during pregnancy when there is a previous history thereof; reocclusion following thrombolytic therapy; chronic arterial obstruction; peripheral vascular disease; acute myocardial infarction; unstable angina; atrial fibrillation; thrombotic stroke; transient ischaemic attacks; disseminated intravascular coagulation; coagulation in extra-corporeal circuits; occlusion of aterio-venous shunts and blood vessel grafts (including coronary artery by-pass grafts); and restenosis and occlusion following angioplasty.

    摘要翻译: 式(I)化合物:抗血栓形成剂,可用于各种治疗领域,包括手术后预防和/或治疗深静脉血栓形成(DVT),主要医学疾病,麻痹,恶性肿瘤,长期固定创伤,应用 下肢石膏或下肢或骨盆骨折; 复发DVT; 怀孕期间DVT有先前的病史; 溶栓治疗后再闭塞; 慢性动脉阻塞; 周边血管疾病; 急性心肌梗塞; 不稳定型心绞痛; 房颤; 血栓性脑卒中 短暂性脑缺血发作; 弥散性血管内凝血; 额外体内循环中的凝血; 静脉分流术和血管移植物(包括冠状动脉旁路移植物)的闭塞; 以及血管成形术后的再狭窄和闭塞。