公开(公告)号：US20180330059A1

公开(公告)日：2018-11-15

申请号：US15590997

申请日：2017-05-09

申请人： James Stewart Bates ,  Julian Phillips

发明人： James Stewart Bates ,  Julian Phillips

IPC分类号： G06F19/00

CPC分类号： G16H10/60 ,  G06F19/324 ,  G06Q10/1095 ,  G16H50/20 ,  G16H50/30

摘要： Presented are systems and methods for providing doctors and patients with treatment information based on computer-aided diagnoses that has been generated using patient input, electronic health care record information, and medical instrument input data. The treatment and/or diagnostic information may be shared with health care professionals and specialists, as needed.

公开(公告)号：US06403371B1

公开(公告)日：2002-06-11

申请号：US09117990

申请日：1998-12-07

申请人： Udo Conrad ,  Ulrike Fielder ,  Julian Phillips ,  Olga Artsaenko

发明人： Udo Conrad ,  Ulrike Fielder ,  Julian Phillips ,  Olga Artsaenko

IPC分类号： C12N1529

CPC分类号： C07K16/16 ,  C07K16/00 ,  C07K2319/00 ,  C12N15/8216 ,  C12N15/8221 ,  C12N15/8257 ,  C12N15/8258

摘要： The invention relates to cassettes for the expression of storable gene products in leaves and specifically in seeds, especially single-chain antibody fragments in leaves and seeds of transgenic tobacco and pea plants. The fields of application of the invention are biotechnology, medicine (diagnosis and therapy), foodstuffs and plant control and agriculture. The expression cassette of the invention comprises constitutive or seed-specific promoters, the LeB4 signal peptide, a gene to be expressed and an ER retention signal. Preference is given to an expression cassette containing the CaMV 35S promoter as the constitutive promoter, the gene for a single-chain antibody fragment as the gene and the amino acid sequence KDEL as the ER retention signal.

摘要翻译： 本发明涉及用于在叶中特异性表达可存储的基因产物的盒，特别是转基因烟草和豌豆植物的叶和种子中的单链抗体片段。 本发明的应用领域是生物技术，医学（诊断和治疗），食品和植物控制和农业。 本发明的表达盒包括组成型或种子特异性启动子，LeB4信号肽，待表达的基因和ER保留信号。 优选含有作为组成型启动子的CaMV 35S启动子的表达盒，单链抗体片段的基因作为基因，氨基酸序列KDEL作为ER保留信号。